Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: - | CAS number: -
Endpoint summary
Administrative data
Description of key information
Additional information
Experimental data on the biodegradability of Reaction mass of dipotassium 2-(3,4-dimethyl-1H-pyrazol-1-yl) succinate and dipotassium 2-(4,5-dimethy-1H-pyrazol-1-yl) succinate are not available.The assessment was therefore based on a study conducted with the conjugate acid Reaction mass of 2-(3,4-dimethyl-1H-pyrazol-1-yl)succinic acid and 2-(4,5-dimethyl-1H-pyrazol-1-yl)succinic acid (CAS 2241455-89-8). The read across approach is in accordance with Regulation (EC) No. 1907/2006, Annex XI, 1.5. Please refer to the analogue justification attached to IUCLID section 13 for a detailed justification.
One ready biodegradation study according to OECD 301 A is available for the source substance Reaction mass of 2-(3,4-dimethyl-1H-pyrazol-1-yl)succinic acid and 2-(4,5-dimethyl-1H-pyrazol-1-yl)succinic acid. No biodegradation was observed during the 28-day test period (<0% based on DOC removal).
The biodegradation of the source substance Reaction mass of 2-(3,4-dimethyl-1H-pyrazol-1-yl)succinic acid and 2-(4,5-dimethyl-1H-pyrazol-1-yl)succinic acid and its metabolite 3,4-dimethylpyrazole (DMP) in soil was investigated in two independent soil degradation studies, conducted following the OECD Guideline 307. A rapid transformation of the test substance to DMP was observed in both studies. In a separate kinetics evaluation conducted with data from the two studies, normalised half-lives of 1.5 - 3.3 days and formation fractions of 0.32 - 0.45 were determined for the transformation of the test substance to DMP. A rapid degradation of DMP, tested in parallel, was recorded with normalised half-lives of 3.8 - 8.9 days. The formation of additional metabolites in soil cannot be excluded. Due to the small size and low complexity of the parent molecule, any potential further metabolites are expected to have a simple structure. These metabolistes are assumed to be rapidly degraded to ubiquitous, short-chained molecules that will finally be mineralised.
Based on the results for the source substance Reaction mass of dipotassium 2-(3,4-dimethyl-1H-pyrazol-1-yl) succinate and dipotassium 2-(4,5-dimethy-1H-pyrazol-1-yl) succinate is considered to be not readily biodegradable in water according to OECD criteria. Nevertheless, it is degraded in soil with a half-life < 4 days and is thus not persistent in the environment. Since the quantitative risk assessment performed for the substance determined no risk for any of the environmental compartments, no further testing on biodegradation is considered necessary.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
