Registration Dossier

Administrative data

Description of key information

The molecule was reliably predicted to be skin sensitizer by the QSAR model.

Key value for chemical safety assessment

Skin sensitisation

Link to relevant study records
skin sensitisation, other
Type of information:
Adequacy of study:
other information
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
Justification for type of information:
The reliability assessment of the prediction is presented in the attached document (QPRF).
equivalent or similar to
other: ECHA guidance on information requirements and chemical safety assessment Chapter R.6: QSARs and grouping of chemicals.
Specific details on test material used for the study:
other: QSAR prediction
Remarks on result:
positive indication of skin sensitisation based on QSAR/QSPR prediction

The prediction was deemed to be reliable on the basis of the parameters listed above. The molecule falls into the applicability domain of the model.

Interpretation of results:
Category 1 (skin sensitising) based on GHS criteria
The molecule is predicted to be skin sensitizer.

Justification for classification or non-classification

Although the molecule was reliably predicted to be a skin sensitizer by VEGA IRFMN model, data available are deemed to be inconclusive for the classification in accordance with CLP regulation.