Registration Dossier

Administrative data

Endpoint:
skin irritation / corrosion, other
Remarks:
ToxTree
Type of information:
other: expert system based on decision tree approach
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
accepted calculation method
Remarks:
ToxTree
Justification for type of information:
Documentation about the justification is provided in attachment (See Supporting information). The reliability assessment of the prediction is presented in the attached document as well (QPRF).

Data source

Reference
Reference Type:
other: Expert system
Title:
ToxTree v.3.1.0
Year:
2018
Bibliographic source:
Skin irritation/skin corrosion decision tree

Materials and methods

Test guideline
Qualifier:
equivalent or similar to
Guideline:
other: ECHA guidance on information requirements and chemical safety assessment Chapter R.6: QSARs and grouping of chemicals.

Test material

Reference
Name:
Unnamed
Type:
Constituent
Specific details on test material used for the study:
O=C1NC(=O)C(N1)(C)C

Results and discussion

In vitro

Results
Irritation / corrosion parameter:
other: ToxTree
Run / experiment:
Not corrosive to skin

Applicant's summary and conclusion

Conclusions:
The substance is predicted to be NON-corrosive to skin.