Registration Dossier

Administrative data

Description of key information

The substance is predicted not to be corrosive to skin by the expert-based model.

Key value for chemical safety assessment

Skin irritation / corrosion

Link to relevant study records
Reference
Endpoint:
skin irritation / corrosion, other
Remarks:
ToxTree
Type of information:
other: expert system based on decision tree approach
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
accepted calculation method
Remarks:
ToxTree
Justification for type of information:
Documentation about the justification is provided in attachment (See Supporting information). The reliability assessment of the prediction is presented in the attached document as well (QPRF).
Qualifier:
equivalent or similar to
Guideline:
other: ECHA guidance on information requirements and chemical safety assessment Chapter R.6: QSARs and grouping of chemicals.
Specific details on test material used for the study:
O=C1NC(=O)C(N1)(C)C
Irritation / corrosion parameter:
other: ToxTree
Run / experiment:
Not corrosive to skin
Conclusions:
The substance is predicted to be NON-corrosive to skin.

Additional information

Justification for classification or non-classification

Although the prediction can exclude the classification of the molecule for skin corrosion, data available are deemed to be inconclusive to exclude the classification as Skin Irrit. 2 in accordance with CLP regulation.

No reliable data are available for eye irritation.