Registration Dossier
Registration Dossier
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EC number: 201-051-3 | CAS number: 77-71-4
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Documentation about the justification is provided in attachment. The molecule is included in the data set of a QSAR model.
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- other: ECHA guidance on information requirements and chemical safety assessment Chapter R.6: QSARs and grouping of chemicals.
- Specific details on test material used for the study:
- CC1(C)NC(=O)NC1=O
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 16 463.45 mg/L
- Remarks on result:
- other: experimental value present in the data set of the model
- Sublethal observations / clinical signs:
Experimental value obtained from a substance included in the dataset of the model.
- Validity criteria fulfilled:
- yes
- Conclusions:
- The LC50 of the substance is 16463.45 mg/L.
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Documentation about the justification is provided in attachment. The molecule is included in the data set of a QSAR model.
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- other: ECHA guidance on information requirements and chemical safety assessment Chapter R.6: QSARs and grouping of chemicals.
- Principles of method if other than guideline:
- The discrimination of excess toxicity from baseline effect: Effect of bioconcentration. LM. Su, X. Liu, Y. Wang, J.J. Li, X.H. Wang, L.X. Sheng, Y.H. Zhao. 2014 Science of the Total Environment 484
- Specific details on test material used for the study:
- O=C1NC(=O)C(N1)(C)C
- Test organisms (species):
- other: Fish
- Dose descriptor:
- LC50
- Effect conc.:
- 16 425.58 mg/L
- Sublethal observations / clinical signs:
Experimental value obtained from a substance included in the test set of the model.
- Validity criteria fulfilled:
- yes
- Conclusions:
- The substance has a fish LC50 of 16425.58 mg/L.
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Documentation about the justification is provided in attachment. The molecule is included in the data set of a QSAR model.
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- other: ECHA guidance on information requirements and chemical safety assessment Chapter R.6: QSARs and grouping of chemicals.
- Specific details on test material used for the study:
- O=C1NC(=O)C(N1)(C)C
- Test organisms (species):
- other: Fish
- Dose descriptor:
- LC50
- Effect conc.:
- >= 100 mg/L
- Remarks on result:
- other: data present in the data set of the model
- Sublethal observations / clinical signs:
Experimental value obtained from a substance included in the dataset of the model.
- Validity criteria fulfilled:
- yes
- Conclusions:
- The substance has a fish LC50 > 100 mg/L.
Referenceopen allclose all
Description of key information
The molecule was present in the data set of the models as experimental value.
The LC50 of the substance is > than 16425 mg/L.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 16 425 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
