Registration Dossier

Environmental fate & pathways

Biodegradation in water: screening tests

Administrative data

Endpoint:
biodegradation in water: ready biodegradability
Type of information:
(Q)SAR
Adequacy of study:
other information
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model, but not (completely) falling into its applicability domain, and documentation / justification is limited
Justification for type of information:
Documentation about the justification is provided in attachment (See Supporting information). The reliability assessment of the prediction is presented in the attached document as well (QPRF)

Data source

Reference
Reference Type:
other: QSAR model
Title:
VEGA in silico platform v.1.1.4
Year:
2017
Bibliographic source:
Ready Biodegradability model (IRFMN) 1.0.9

Materials and methods

Test guideline
Qualifier:
equivalent or similar to
Guideline:
other: ECHA guidance on information requirements and chemical safety assessment Chapter R.6: QSARs and grouping of chemicals.

Test material

Reference
Name:
Unnamed
Type:
Constituent
Specific details on test material used for the study:
CC1(C)NC(=O)NC1=O

Results and discussion

% Degradation
Parameter:
probability of ready biodegradability (QSAR/QSPR)
Remarks:
Predicted as Possible Readily Biodegradable
Remarks on result:
other: Predicted with VEGA IRFMN model

Any other information on results incl. tables

The prediction was deemed to be not reliable on the basis of the parameters listed above. The molecule does not fall into the applicability domain of the model.

Applicant's summary and conclusion

Validity criteria fulfilled:
not applicable
Interpretation of results:
other: the result was not taken into further consideration
Conclusions:
The substance was predicted to be possible readily biodegradable.