Registration Dossier

Administrative data

Endpoint:
acute toxicity: inhalation
Data waiving:
other justification
Justification for data waiving:
the study does not need to be conducted because exposure of humans via inhalation is not likely taking into account the vapour pressure of the substance and/or the possibility of exposure to aerosols, particles or droplets of an inhalable size
Cross-reference
Reason / purpose:
data waiving: supporting information
Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
September 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
GLP compliance:
no
Type of method:
dynamic method
Specific details on test material used for the study:
Batch-no.: 05347/MA
Key result
Temp.:
20 °C
Remarks on result:
other: calculated
Remarks:
1.57E-16 kPa
Key result
Temp.:
50 °C
Remarks on result:
other: calculated
Remarks:
1.64E-13 kPa

Experimental vapour pressure data:

 T [K]  P [kPa]
 539.59  0.092

 542.66

 0.11

 546.03

 0.16

 550.29

 0.21

 555.94

 0.29

 559.22

 0.40

 564.27

 0.56

 565.09

 0.60

566.71

 0.65

 568.80

 0.74

 570.40

 0.85

 575.02

 1.14

 576.08

 1.23

 577.81

 1.39

 583.09

 1.94

 585.10

 2.16

 594.23

 3.73

 595.19  4.02
Conclusions:
Calculated vapour pressure at 20 °C 1.57 E-16 kPa and at 50 °C 1.64 E-13 kPa.
Values are afflicted with high relative uncertainties.
Executive summary:

The vapour pressure was measured with OECD 104 guideline method in a temperature range from 539.59 K to 595.19 K. To the experimental data Antoine parameters were fitted. Calculated values at 20 and 50 °C are given.

Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion