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EC number: 949-745-1
CAS number: -
The substance is highly unsoluble in water
and therefore no effects within the limit of water solubility are
expected. This has been confirmed in the available acute aquatic
toxicity study in Daphnia magna. And it is further supported by
three available acute fish studies where the analogue substances was
found to be not toxic under test conditions in the range of water
Three studies were conducted with the
analogue test substance 1,2,4 -Benzenetricarboxylic acid, mixed decyl
and octyl triesters in different fish species.
In the first study the acute toxicity of
1,2,4 -Benzenetricarboxylic acid, mixed decyl and octyl triesters to
Zebra fish (Brachydanio rerio) was determined in a 96 -hour static test
according to the Commision Directive 92/96/EEC, Annex Part C.1, dated
December 29, 1992 and the OECD Guideline for Testing of Chemicals No.
203, adopted July 17, 1992. The test was performed in compliance with
Good Laboratory Practice Regulations. Due to the low water solubility
limit of the test substance a filtrate of a 1 g/L in tap water (stirring
for 18 hours) was tested. Analytical verification was done by means of
DOC determination. The measured values of the test solutions after 24
hours deviated more than 20% from the values of the freshly prepared
solutions. Therefore the geometric mean (3.0 mg/L) of the these
solutions were used for evaluation. Additionally a control was tested in
parallel. No lethality of Brachydanio rerio was observed at the tested
concentration after 96 hours exposure.
In a second study the LC50 of 1,2,4
-Benzenetricarboxylic acid, mixed decyl and octyl triesters was greater
than 1 mg/L, tested with Salmo gaidneri.
In a third supporting study the acute
toxicity of the test item to the freshwater fish rainbow trout
(Oncorhynchus mykiss) has been investigated and gave a 96-Hour LL50
value of greater than 100 mg/L loading rate WAF. The No Observed Effect
Loading rate was 100 mg/L loading rate WAF.
Therefore the analogu substance was not
toxic under test conditions in the range of water solubility towards
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