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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Link to relevant study record(s)

Description of key information

After 21 days of exposure of Daphnia magna the LC50 was determined to be 3.54 mg/L, the NOEC was determined to be 0.59 mg/L and the LOEC to be 1.93 mg/L.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
0.59 mg/L

Additional information

A reproduction study with Daphnia magna was published by the Ministery of Environment, Japan. In a 21-day study conducted according to OECD 211, 10 daphnids per test group were tested in a semi-static test setup with daily renewal of the medium. Five test concentration 0.100, 0.320, 1.00, 3.20, 10.0 mg/L, and a control were run. The concentration of the test item in the test solutions was determined with Gas chromatography - mass spectrometry (GC/MS). The percentage of measurement concentration to nominal concentration was 61 to 75% at test solution preparation and 39 to 67% before renewal. The main cause of the decrease was assumed to be due to the volatilization from water. After 21 days of exposure the LC50 was determined to be 3.54 mg/L, the NOEC was determined to be 0.59 mg/L and the LOEC to be 1.93 mg/L. An EC50 value was extrapolated to be 3.59 mg/L, which supports the result obtained in the short-term study with Daphnia magna.