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Physical & Chemical properties

Partition coefficient

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
Febr. 7, 2019 - Febr. 8, 2019
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
GLP compliance:
no
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Analytical method:
high-performance liquid chromatography
Key result
Type:
log Pow
Partition coefficient:
2.2
Temp.:
25 °C
pH:
ca. 6

Using the correlation log k / log POW, the log POW of the test item Ethylphthalyl ethyl glycolate was calculated as 2.2 ± 0.0 (mean ± standard deviation) at 25 ± 0.5 °C and a pH of ca. 6.

The validity criteria and results are presented in the following table:

Validity Criteria and Results

Peak

Parameter

Criterion

Found

Assessment

1

Range (Max – Min. log POW)

< 0,1

0.001

valid

Value within Range of Reference Items

0.30 - 3.60

2.215

valid

The correlation log k / log POWis good: the coefficient of determination r2 was calculated as 0.9582. This value was considered as sufficiently high to use the calibration function for the determination of the log POW of the test item Ethylphthalyl ethyl glycolate.

Conclusions:
The log pow of Ethylphthalyl ethyl glycolate was determined using the HPLC method according to OECD 117. The partitioning coefficient of the test item was stated as 2.2 at 25 ± 0.5 °C and a pH of ca. 6.

Description of key information

The log pow of Ethylphthalyl ethyl glycolate  was determined using the HPLC method according to OECD 117. The partitioning coefficient of the test item  was stated as 2.2 at  25 ± 0.5 °C and a pH of ca. 6.

Key value for chemical safety assessment

Log Kow (Log Pow):
2.2
at the temperature of:
25 °C

Additional information