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Physical & Chemical properties

Melting point / freezing point

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Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
03-25 April 2006
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Remarks:
The study was conducted according to an internationally recognised method, and under GLP. No deviation affected the quality of the study. The substance is considered to be adequately characterised. Therefore full validation applies.
Qualifier:
according to
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Deviations:
no
Principles of method if other than guideline:
Not applicable
GLP compliance:
yes (incl. certificate)
Remarks:
signed 24 February 2006
Type of method:
differential scanning calorimetry
Key result
Melting / freezing pt.:
-111.4 °C
Decomposition:
no

Table 4.2/1: Melting point – results

 

Test No.

Start temperature

Heating rate

Onset temperature

1

-120 °C

+5 °C/min

-111.4 °C

2

-120 °C

+5 °C/min

-111.3 °C

Mean± S.D.

-111.4 ± 0.1 °C

Executive summary:

The melting point of the test substance was determined under GLP according to EU A.1 guideline, using Differential Scanning Calorimetry. Two main runs were performed and found consistent, so the mean final temperature was retained.

The melting temperature of test substance has been determined to be -111.4 ± 0.1 °C.

Description of key information

Measured melting point (i.e. transition from solid to liquid) = -111.4°C.

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:
-111.4 °C

Additional information

A fully reliable experimental study, conducted according to a recognized EC method and under GLP, is available. Therefore it is considered as a key study, and the result is retained as key data.