Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

First-aid measures

Eye Contact: Flush eyes continuously with water for at least 15 minutes and obtain immediate medical attention.

Skin Contact: Wash skin with soap and water. If irritation occurs or persists, get medical attention.

Ingestion: In the event of swallowing this material, seek immediate medical attention. DO NOT INDUCE VOMITING. Do not induce vomiting unless directed by medical personnel.

Inhalation: Remove to fresh air. Keep patient at rest. Get medical attention immediately

Fire-fighting measures

Extinguishing Media: Use water spray, foam, dry powder, or carbon dioxide.

Special Hazards Arising from the Substance or Mixture

Hazardous Combustion Products: This material produces toxic fumes of nitrogen and sulfur oxides, carbon dioxide, and carbon monoxide during fires.

Fire / Explosion Hazards: High sensitivity of a dust cloud to ignition, based on minimum ignition energy.

Advice for Fire-Fighters

Wear approved positive pressure, self-contained breathing apparatus and full protective turn out gear.

Additional Information: Toxic or corrosive gases are expected from fires involving this material.

Accidental release measures

Personal Precautions, Protective Equipment and Emergency Procedures

Personnel involved in clean-up should wear appropriate personal protective equipment (see Section 8). Minimize exposure. Eliminate all sources of ignition and ventilate area using explosion-proof equipment.

Environmental Precautions

Place waste in an appropriately labeled, sealed container for disposal. Care should be taken to avoid environmental release.

Methods and Material for Containment and Cleaning Up/Measures for Cleaning/Collecting:

Contain the source of the spill if it is safe to do so. Collect spilled material by a method that controls dust generation. Clean spill area thoroughly. Avoid use of a filtered vacuum to clean spills of dry solids, due to the potential for electrostatic discharge and the strong dust explosion characteristic and high sensitivity to ignition.

Additional Consideration for Large Spills: Non-essential personnel should be evacuated from affected area. Report emergency situations immediately. Clean up operations should only be undertaken by trained personnel.

Handling and storage

Precautions for Safe Handling

Ground and bond all bulk transfer equipment. Avoid open handling. Minimize dust generation. Use local exhaust ventilation or perform work under fume hood/fume cupboard. Avoid inhalation and contact with skin, eye, and clothing. When handling, use appropriate personal protective equipment (see Section 8). Wash hands and any exposed skin after removal of PPE. Eliminate possible ignition sources (e.g., heat, sparks, flame, impact, friction, electricity), and follow appropriate grounding and bonding procedures. Avoid contact with eyes, skin and clothing. Avoid breathing dust. Minimize dust generation and accumulation. Use with adequate ventilation. All conductive elements of the system that contact the dry substance should be properly bonded and grounded and equipped with proper explosion relief or suppression systems. This material should not be flowed through nonconductive ducts or pipes because of the potential for electrostatic discharge ignition. Restricting the use of high resistivity

materials, such as plastics, should be considered. Releases to the environment should be avoided. Review and implement appropriate technical and procedural waste water and waste disposal measures to prevent occupational exposure or environmental releases. Potential points of process emissions of this material to the atmosphere should be controlled with dust collectors, HEPA filtration systemsor other equivalent controls.

Conditions for Safe Storage, Including any Incompatibilities

Storage Conditions: Keep container tightly closed when not in use.

Storage Temperature: Store at room temperature

Transport information

Land transport (UN RTDG/ADR/RID)

UN number:
Not regulated under ADR/RID
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Inland waterway transport (UN RTDG/ADN(R))

UN number:
Not regulated under ADN(R)
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Marine transport (UN RTDG/IMDG)

UN number:
Not regulated under IMDG
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Air transport (UN RTDG/ICAO/IATA)

UN number:
Not regulated under ICAO/IATA
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Exposure controls / personal protection

Pfizer OEL TWA-8 Hr:       600 μg/m³, Sensitizer

Analytical Method:       Analytical method available. Contact Pfizer Inc for further information.

Exposure Controls Engineering Controls: Engineering controls should be used as the primary means to control exposures. Use process containment, local exhaust ventilation, or other engineering controls to maintain airborne levels below recommended exposure limits.

Personal Protective Equipment: Refer to applicable national standards and regulations in the selection and use of personal protective equipment (PPE).Contact your safety and health professional or safety equipment supplier for assistance in selecting the correct protective clothing/equipment based on an assessment of the workplace conditions, other chemicals used or present in the workplace and specific operational processes.

Hands: Wear impervious gloves to prevent skin contact.

Eyes: Wear safety goggles as minimum protection.

Skin: Wear impervious protective clothing to prevent skin contact - consider use of disposable clothing where appropriate.

Respiratory protection: If the applicable Occupational Exposure Limit (OEL) is exceeded, wear an appropriate respirator with a protection factor sufficient to control exposures to below the OEL.

Stability and reactivity

Reactivity: No data available

Chemical Stability: Stable at room temperature if protected from moisture. Stable below 170°C.

Possibility of Hazardous Reactions

Oxidizing Properties:       None expected under normal and foreseeable conditions of use

Conditions to Avoid:       Moisture, acids. Keep away from heat and other sources of ignition, including electrostatic discharge.

Incompatible Materials:       As a precautionary measure, keep away from strong oxidizers

Hazardous Decomposition Products:       None expected under normal conditions.

Disposal considerations

Dispose of waste in accordance with all applicable laws and regulations. Member State specific and Community specific provisions must be considered. Considering the relevant known environmental and human health hazards of the material, review and implement appropriate technical and procedural waste water and waste disposal measures to prevent occupational exposure and environmental release. It is recommended that waste minimization be practiced. The best available technology should be utilized to prevent environmental releases. This may include destructive techniques for waste and wastewater.