Registration Dossier
Registration Dossier
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Diss Factsheets
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EC number: 246-608-1 | CAS number: 25088-57-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Administrative data
First-aid measures
Get medical attention immediately. Show Safety Data Sheet to the medical personnel.
- Following inhalation:
Remove affected person from source of contamination. Move affected person to fresh air and keep warm and at rest in a position comfortable for breathing. Maintain an open airway. Loosen tight clothing such as collar, tie or belt. When breathing is difficult, properly trained personnel may assist affected person by administering oxygen. Place unconscious person on their side in the recovery position and ensure breathing can take place.
- Following skin contact:
Rinse with water.
- Following eye contact:
Rinse immediately with plenty of water. Remove any contact lenses and open eyelids wide apart. Continue to rinse for at least 10 minutes.
- Following ingestion:
Rinse mouth thoroughly with water. Remove any dentures. Give a few small glasses of water or milk to drink. Stop if the affected person feels sick as vomiting may be dangerous. Do not induce vomiting unless under the direction of medical personnel. If vomiting occurs, the head should be kept low so that vomit does not enter the lungs. Never give anything by mouth to an unconscious person. Move affected person to fresh air and keep warm and at rest in a position comfortable for breathing. Place unconscious person on their side in the recovery position and ensure breathing can take place. Maintain an open airway. Loosen tight clothing such as collar, tie or belt.
- Most important symptoms and effects:
General information - The severity of the symptoms described will vary dependent on the concentration and the length of exposure.
Inhalation - Prolonged inhalation of high concentrations may damage respiratory system.
Ingestion - May cause irritation.

Skin contact - Redness. Irritating to skin.
Eye contact - Irritating to eyes.
Fire-fighting measures
The product is not flammable. Extinguish with alcohol-resistant foam, carbon dioxide, dry powder or water fog. Use fire-extinguishing media suitable for the surrounding fire.
- Unsuitable extinguishing media:
Do not use water jet as an extinguisher, as this will spread the fire.
- Special hazards arising from the substance or mixture:
Containers can burst violently or explode when heated, due to excessive pressure build-up. Thermal decomposition or combustion products may include the following substances: Harmful gases or vapours.
- Advice for fire fighter:
Avoid breathing fire gases or vapours. Evacuate area. Keep upwind to avoid inhalation of gases, vapours, fumes and smoke. Ventilate closed spaces before entering them. Cool containers exposed to heat with water spray and remove them from the fire area if it can be done without risk. Cool containers exposed to flames with water until well after the fire is out. If a leak or spill has not ignited, use water spray to disperse vapours and protect men stopping the leak. Control run-off water by containing and keeping it out of sewers and watercourses. If risk of water pollution occurs, notify appropriate authorities.
Wear positive-pressure self-contained breathing apparatus (SCBA) and appropriate protective clothing. Firefighter's clothing conforming to European standard EN469 (including helmets, protective boots and gloves) will provide a basic level of protection for chemical incidents.
Accidental release measures
No action shall be taken without appropriate training or involving any personal risk. Keep unnecessary and unprotected personnel away from the spillage. Wear protective clothing as described in Section 8 of this safety data sheet. Follow precautions for safe handling described in this safety data sheet. Wash thoroughly after dealing with a spillage. Ensure procedures and training for emergency decontamination and disposal are in place. Do not touch or walk into spilled material.
- Environmental precautions:
Immiscible with water. Aquatic toxicity is unlikely to occur. However, large or frequent spills may have hazardous effects on the environment. Absorb spillage with non-combustible, absorbent material. Avoid discharge into drains or watercourses or onto the ground. Avoid discharge to the aquatic environment. Large Spillages: Inform the relevant authorities if environmental pollution occurs (sewers, waterways, soil or air).
- Methods and material for containment and cleaning up:
Wear protective clothing as described in Section 8 of this safety data sheet. Clear up spills immediately and dispose of waste safely. Approach the spillage from upwind. Small Spillages: If the product is soluble in water, dilute the spillage with water and mop it up. Alternatively, or if it is not water-soluble, absorb the spillage with an inert, dry material and place it in a suitable waste disposal container. Large Spillages: If leakage cannot be stopped, evacuate area. Flush spilled material into an effluent treatment plant, or proceed as follows. Contain and absorb spillage with sand, earth or other non-combustible material. Place waste in labelled, sealed containers. Clean contaminated objects and areas thoroughly, observing environmental regulations. The contaminated absorbent may pose the same hazard as the spilled material. Flush contaminated area with plenty of water. Wash thoroughly after dealing with a spillage. Dispose of waste to licensed waste disposal site in accordance with the requirements of the local Waste Disposal Authority.
Handling and storage
Read and follow manufacturer's recommendations. Wear protective clothing as described in Section 8 of the safety data sheet. Keep away from food, drink and animal feeding stuffs. Handle all packages and containers carefully to minimise spills. Keep container tightly sealed when not in use. Avoid the formation of mists. Suspected of causing genetic defects. Do not handle until all safety precautions have been read and understood. Do not handle broken packages without protective equipment. Do not reuse empty containers.
- Conditions for safe storage, including any incompatibilities:
Store away from incompatible materials. Store in accordance with local regulations. Keep only in the original container. Keep container tightly closed, in a cool, well ventilated place. Keep containers upright. Protect containers from damage. Bund storage facilities to prevent soil and water pollution in the event of spillage. The storage area floor should be leak-tight, jointless and not absorbent.
Transport information
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Marine transport (UN RTDG/IMDG)
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Exposure controls / personal protection
Provide adequate ventilation. Personal, workplace environment or biological monitoring may be required to determine the effectiveness of the ventilation or other control measures and/or the necessity to use respiratory protective equipment. Use process enclosures, local exhaust ventilation or other engineering controls as the primary means to minimise worker exposure. Personal protective equipment should only be used if worker exposure cannot be controlled adequately by the engineering control measures. Ensure control measures are regularly inspected and maintained. Ensure operatives are trained to minimise exposure.
2. Organisational protection measures
See above.
3. Hand protection
Chemical-resistant, impervious gloves complying with an approved standard should be worn if a risk assessment indicates skin contact is possible. The most suitable glove should be chosen in consultation with the glove supplier/manufacturer, who can provide information about the breakthrough time of the glove material. To protect hands from chemicals, gloves should comply with European Standard EN374. Considering the data specified by the glove manufacturer, check during use that the gloves are retaining their protective properties and change them as soon as any deterioration is detected. Frequent changes are recommended.
4. Feet protection
Appropriate footwear and additional protective clothing complying with an approved standard should be worn if a risk assessment indicates skin contamination is possible.
5. Body protection
Appropriate footwear and additional protective clothing complying with an approved standard should be worn if a risk assessment indicates skin contamination is possible.
6. Eye protection
Eyewear complying with an approved standard should be worn if a risk assessment indicates eye contact is possible. Personal protective equipment for eye and face protection should comply with European Standard EN166. Wear tight-fitting, chemical splash goggles or face shield. If inhalation hazards exist, a full-face respirator may be required instead.
7. Respiratory protection
Respiratory protection complying with an approved standard should be worn if a risk assessment indicates inhalation of contaminants is possible. Ensure all respiratory protective equipment is suitable for its intended use and is ‘CE’-marked. Check that the respirator fits tightly and the filter is changed regularly. Gas and combination filter cartridges should comply with European Standard EN14387. Full face mask respirators with replaceable filter cartridges should comply with European Standard EN136. Half mask and quarter mask respirators with replaceable filter cartridges should comply with European Standard EN140.
Stability and reactivity
No potentially hazardous reactions known.
2. Chemical stability
Stable at normal ambient temperatures and when used as recommended. Stable under the prescribed storage conditions.
3. Possibility of hazardous reactions
No potentially hazardous reactions known.
4. Conditions to avoid
There are no known conditions that are likely to result in a hazardous situation.
5. Incompatible materials
No specific material or group of materials is likely to react with the product to produce a hazardous situation.
6. Hazardous decomposition products
Does not decompose when used and stored as recommended. Thermal decomposition or combustion products may include the following substances: Harmful gases or vapours.
Disposal considerations
The generation of waste should be minimised or avoided wherever possible. Reuse or recycle products wherever possible. This material and its container must be disposed of in a safe way. Disposal of this product, process solutions, residues and by-products should at all times comply with the requirements of environmental protection and waste disposal legislation and any local authority requirements. When handling waste, the safety precautions applying to handling of the product should be considered. Care should be taken when handling emptied containers that have not been thoroughly cleaned or rinsed out. Empty containers or liners may retain some product residues and hence be potentially hazardous.
Disposal methods
Do not empty into drains. Dispose of surplus products and those that cannot be recycled via a licensed waste disposal contractor. Waste, residues, empty containers, discarded work clothes and contaminated cleaning materials should be collected in designated containers, labelled with their contents. Incineration or landfill should only be considered when recycling is not feasible.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.