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Physical & Chemical properties

Water solubility

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water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
28 Nov 2017 to 14 Dec 2017
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
according to guideline
OECD Guideline 105 (Water Solubility)
Version / remarks:
according to guideline
EPA OPPTS 830.7860 (Water Solubility Generator Column Method)
Version / remarks:
GLP compliance:
yes (incl. QA statement)
Type of method:
column elution method
Specific details on test material used for the study:
- Name of test material (as cited in study report): NDBC
- Source: Performance Additives Italy
- Appearance: Solid
- Storage conditions: Under ambient conditions in the dark
Key result
Water solubility:
8.93 µg/L
Conc. based on:
test mat.
Incubation duration:
15 d
20 °C
Details on results:
Under the instrumental conditions presented, the measured reagent water solubility of NDBC was 8.93 μg/L. The generator column apparatus was allowed to equilibrate for 15 days due to a downward trend in test substance solubility values over the course of the test. The magnitude of this decrease was significantly reduced with time. The test was terminated after analyzing the Day 15 samples, even though the protocol criteria requiring that five consecutive samples at each flow rate have a CV of <10%, and that the percent difference between the mean measured concentrations for each flow rate be 30% or less were not met. For all practical purposes, the test substance concentrations in the water solubility samples had stabilized within the single ppb range and in the scientific judgement of the Study Director, the mean value determined following this extended equilibration period was representative of the overall test substance water solubility. The matrix blank sample did not show any interferences.

Description of key information

The water solubility of the test item was determined to be 8.93 µg/L at 20 ± 0.1 °C and pH 5.88

Key value for chemical safety assessment

Water solubility:
8.93 µg/L
at the temperature of:
20 °C

Additional information