2-(methoxymethyl)-3-methyl-aniline

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:

short-term toxicity to aquatic invertebrates

Type of information:

calculation (if not (Q)SAR)

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: see 'Remark'

Remarks:

Reliable predicted value obtained by the OECD QSAR Toolbox using trend analysis within category members.The prediction fulfilling the OECD criteria for the validation of QSAR models with respect to • a defined endpoint • unambiguous algorithm • a defined domain of applicability • appropriate measure of goodness-of-fit, robustness and predictivity

Data source

Reference

Reference Type:

other: OECD QSAR Toolbox Report

Title:

Unnamed

Year:

2018

Materials and methods

Principles of method if other than guideline:

Calculation using QSAR Toolbox based on trend analysis within category members.

GLP compliance:

no

Test material

Test material information

Constituent 1

Reference substance name:

2-(methoxymethyl)-3-methyl-aniline

EC Number:

821-826-5

Cas Number:

1472650-01-3

Molecular formula:

C9 H13 N O

IUPAC Name:

2-(methoxymethyl)-3-methyl-aniline

Test material form:

liquid

Sampling and analysis

Analytical monitoring:

not required

Test organisms

Test organisms (species):

Daphnia magna

Study design

Total exposure duration:

48 h

Results and discussion

Effect concentrations

Duration:

48 h

Dose descriptor:

EC50

Effect conc.:

2.27 mg/L

Nominal / measured:

estimated

Conc. based on:

test mat.

Basis for effect:

behaviour