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Physical & Chemical properties

Melting point / freezing point

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Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
19-08-2014 to 19-11-2014
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Guideline study performed under GLP. All relevant validity criteria were met.
Qualifier:
according to
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Deviations:
no
Qualifier:
according to
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Deviations:
no
Qualifier:
equivalent or similar to
Guideline:
EPA OPPTS 830.7200 (Melting Point / Melting Range)
Deviations:
no
Qualifier:
equivalent or similar to
Guideline:
other: CIPAC MT 1 (2009): Freezing Point
Deviations:
not applicable
GLP compliance:
yes (incl. certificate)
Remarks:
inspected: January 2013; signature: March 2013
Type of method:
thermal analysis
Melting / freezing pt.:
ca. -75.4 °C
Atm. press.:
> 1 004.2 - < 1 006.7 hPa
Decomposition:
no
Sublimation:
no
Remarks on result:
other: Mean melting point (n=2) ; with onset temperatures not deviating by more than 0.5 K in duplicate

Table 1.0 : Results of DSC Measurements

Sample

Sample

weight / mg

Onset

of Effect

/ °C

Range of effect / °C

Remark

Atmospheric pressure

/ hPa

1

27.46

-75.19
286.02

-80 to -60 (endo)
220 to 320 (endo)

#1

1006.7

2

22.13

-75.53
290.16

-80 to -55 (endo)
240 to 350 (endo)

#1

1004.2

#1: During cooling to -100°C no thermal effects detected.

Conclusions:
The melting point of the test item has been determined to be: -75.4 ±0.5 °C.
Executive summary:

The melting/freezing temperature was determined using EU Method A.1 and OECD TG 102 Differential Scanning Calorimetry method under GLP. During cooling to -100°C no thermal effects were detected. During the heating phase a distinct endothermic effect was observed in the temperature range of -80 to -55 °C in duplicate, which can be associated with the melting of the test item. As the onset temperatures in both tests deviate by more than 0.5 K (or 0.5 °C) from their mean value, the test item has a melting point of -75.4°C at atmospheric pressure (1013 hPa).

Description of key information

Mp: -75.4 °C or 197.75 K (< -20 °C) at 1 atm, EU Method A.1 - DSC method, 2014

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:
-75.4 °C

Additional information

The melting/freezing temperature was determined using EU Method A.1 and OECD TG 102 Differential Scanning Calorimetry method under GLP. During cooling to -100°C no thermal effects were detected. During the heating phase a distinct endothermic effect was observed in the temperature range of -80 to -55 °C in duplicate, which can be associated with the melting of the test item. As the onset temperatures in both tests deviate by more than 0.5 K (or 0.5 °C) from their mean value, the test item has a melting point of -75.4°C at atmospheric pressure (1013 hPa).