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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Description of key information

The substance is acutely toxic to algae.

The lowest 72-h ErC50 (2907 µg V/L, meas.) and ErC10 values (716 µg V/L, meas.) for growth rate of the green alga Scenedesmus subspicatus were observed for V2O5 flakes (Mitterer, 1999; Klimisch 2).

Corrected for the molecular weight of divanadyl pyrophosphate (CAS no. 65232 -89 -5): 72 -h ErC50 = 8782 µg/L; 72 -h ErC10 = 2163 µg/L.

Key value for chemical safety assessment

EC50 for freshwater algae:
8 782 µg/L
EC10 or NOEC for freshwater algae:
2 163 µg/L

Additional information

Since only a study on the long-term toxicity of divanadyl pyrophosphate (CAS no. 65232 -89 -5) to aquatic algae, rated as supporting, is available, a read-across approach to structurally similar pentavalent vanadium substances was performed.

Three reliable guideline studies were performed with three different pentavalent vanadium substances by Mitterer (1999). The test species was Desmodesmus subspicatus. The tests were performed according to OECD 201 and EU method C.3 under GLP conditions. The test concentrations were analytically verified by monitoring the vanadium concentrations in the medium. The test duration was 72 hours. Biomass and growth rate were observed. The lowest effect values were recorded for divanadium pentaoxide (CAS 1314-62-1).

Table: Observed endpoints for Desmodesmus subspicatus (measured)

Test substance

report no.

Endpoint

Concentration [µg/L]

Remark

CAS 1314-62-1

11920-99

72-h ErC10

716

Growth rate; Key study

CAS 1314-62-1

11920-99

72-h ErC50

2907

Growth rate; Key study

CAS 1314-62-1

11920-99

72-h NOEC

16.8

Biomass; Key study

CAS 1314-62-1

11920-99

72-h EbC50

989

Biomass; Key study

CAS 13718-26-8

11921-99

72-h ErC10

4342

Growth rate; Supporting study

CAS 13718-26-8

11921-99

72-h ErC50

7619

Growth rate; Supporting study

CAS 13718-26-8

11921-99

72-h NOEC

75

Biomass; Supporting study

CAS 13718-26-8

11921-99

72-h EbC50

2177

Biomass; Supporting study

CAS 12207-63-5

11922-99

72-h ErC10

1796

Growth rate; Supporting study

CAS 12207-63-5

11922-99

72-h ErC50

3865

Growth rate; Supporting study

CAS 12207-63-5

11922-99

72-h NOEC

30

Biomass; Supporting study

CAS 12207-63-5

11922-99

72-h EbC50

1162

Biomass; Supporting study

 

Further information are available for CAS 13718-26-8. Miramand & Unsai (1978) published data on the toxicity of the substance to marine algae. However, the tests did not followed a standard guideline and the test method was poorly described. In addition, no statistics were provided. The test concentrations were not monitored. The exposure period (15 days) and the endpoint are not relevant (mortality) for algae. Therefore, the information are not reliable and were disregarded.

A study with Pseudokirchneriella subcapitata investigated the effect of E-326 catalyst (CAS no. 65232 -89 -5). The study was performed according to OECD 201 under GLP (BASF SE, 1998; report no. HUT004/982383). The study is taken into account as supportive information.

For the assessment of the toxicity of divanadyl pyrophosphate (CAS no. 65232 -89 -5), the effect values based on the vanadium concentration must be corrected for the molecular weight of divanadyl pyrophosphate (33.1 % V). Corrected for the molecular weight of divanadyl pyrophosphate (CAS no. 65232 -89 -5): 72-h ErC50 = 8782 µg/L (= 2907 µg V/L); 72-h ErC10 = 2163 µg/L (= 716 µg V/L).

It can be concluded that the substance is acutely toxic to algae.