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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Administrative data

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Description of key information

For acute toxicity (EC50) in algae, VEGA/ProtoQSAR classification model predicts the compound as“NON-Toxic” (i.e. LC50 > 10 mg/l), associated to low reliability. Similarly, VEGA/ProtoQSAR regression model provides prediction of 128.59 mg/l, thus resulting in agreement with VEGA/ProtoQSAR classification model (ADI = 0.355). However, both models reports experimental value as “toxic” for the most similar compound with SMILES N#CC=CC(F)(F)F. The toxicity of such
compound may be triggered by the triple bond N#C, not present in the target compound. In any case, we cannot exclude a toxicity for the target compound based on read-across considerations.
Overall assessment. The predictions for acute toxicity in algae are consistent among each other, although low reliability is associated to both predictions and they are not supported by read-across considerations. The compound of concernmay be not toxicto algae (LC50 > 100 mg/l) but with a high uncertainty.

Key value for chemical safety assessment

EC50 for freshwater algae:
128.59 mg/L

Additional information