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Physical & Chemical properties

Water solubility

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Description of key information

The Water Solubility IRFMN model of VEGA platform provides prediction of 1.89 [-log(mol/l)] (1475.39 mg/l) associated with low reliability. The three most similar compounds to (1Z)-1,3,3,3- Tetrafluoroprop-1-ene are shown in the VEGA/IRFMN model (Figure 1), reporting a water solubility between 1.1 and 2.7 -log(mol/L). However, the target compound is out of the Applicability Domain of the model, reporting AD index = 0.481. EPIsuite model provides prediction of 1.75 [-log(mol/L)]
i.e. 2010 mg/l for water solubility (at 25 °C). Similarly, T.E.S.T. model provides prediction of 1.79 [- log(mol/L)] for the target compound.
Overall assessment: The predictions for water solubility are quite consistent among the three models, although a low reliability is associated to all results. However, it is likely to be consider a water solubility between 1.75 and 1.89 [-log(mol/l)], thus corresponding to1475 and 2010 mg/L.

Key value for chemical safety assessment

Water solubility:
1 475 mg/L
at the temperature of:
25 °C

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