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Physical & Chemical properties

Partition coefficient

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Description of key information

With regard to LogP (Octanol–Water Partition Coefficient), the VEGA/Meylan/Kowwin, VEGA/MLogP and VEGA/ALogP models provide prediction of 2.01, 2.08 and 1.4, associated with low reliability mainly due to the lack of similar compounds. However, the target compound is likely to be out of the Applicability Domain of the models and the AD index is 0.75.
Overall assessment: The predictions for LogP are quite consistent among each other, although a low reliability is associated to all results. Therefore, a LogP value between1.8 and 2.0 can be considered for (1Z)-1,3,3,3-Tetrafluoroprop-1-ene, by taking into account similar compound with SMILES FC(F)(F)C(F)(F)F for which an experimental value is available (logP = 2), within a weight-of-evidence strategy combining results of in silico models and read-across.

Key value for chemical safety assessment

Log Kow (Log Pow):
2

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