Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

In the key study the test substance was found to be moderately toxic to mice following intraperitoneal injection. There were no adverse effects noted in any animal receiving intraperitoneal control doses with distilled water. There was no evidence that the test substance either suppressed or stimulated proliferation of polychromatophilic erythrocytes.

LD50 (males) 354 mg/kg

LD50 (females) 374 mg/kg

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Endpoint conclusion:
adverse effect observed
Dose descriptor:
LD50
Value:
354 mg/kg bw

Additional information

Justification for classification or non-classification

According to the criteria in CLP Annex I, 3.1.2 to 3.1.3.4, a substance is a Category 4 for acrute toxicioty if it has an Oral LD50 >300 but = 2000 mg/kg bodyweight.

DDPA has an LD50 (males) of 354 mg/kg, and LD50 (females) of 374 mg/kg, therefore is considered a Category 4 for acute toxicity.