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Ecotoxicological information

Short-term toxicity to fish

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Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
1974
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions
Qualifier:
equivalent or similar to guideline
Guideline:
other: FC 2.463, 1-7-1973
Deviations:
not specified
GLP compliance:
no
Analytical monitoring:
no
Vehicle:
no
Test organisms (species):
other: Rainbow trout
Details on test organisms:
No details available
Limit test:
no
Total exposure duration:
48 h
Post exposure observation period:
None
Hardness:
No data available
Test temperature:
No data available
pH:
No data available
Dissolved oxygen:
No data available
Salinity:
Not applicable
Conductivity:
No data available
Nominal and measured concentrations:
100, 200 & 1000 mg/L
Details on test conditions:
None
Reference substance (positive control):
no
Duration:
48 h
Dose descriptor:
other: TL0
Effect conc.:
> 1 000 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Key result
Duration:
48 h
Dose descriptor:
other: TL50
Effect conc.:
> 1 000 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Duration:
48 h
Dose descriptor:
other: TL100
Effect conc.:
> 1 000 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Details on results:
None
Results with reference substance (positive control):
None
Reported statistics and error estimates:
None
Sublethal observations / clinical signs:

No mortality was observed at the tested concentrations.

Validity criteria fulfilled:
yes
Conclusions:
The LC50 of FAT 11127/A in this fish acute toxicity test was determined to be greater than 1000 mg/L.
Executive summary:

The acute fish toxicity test was performed using a methodology equivalent or similar to OECD Guideline 203. Rainbow trout were used in this test, which were exposed to FAT 11127/A for 48 hours at following concentrations: 100, 200 and 1000 mg/L. No mortality was observed at the tested concentrations. Hence, the LC50 of FAT 11127/A in this fish acute toxicity test was determined to be greater than 1000 mg/L.

Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1979
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions
Qualifier:
according to guideline
Guideline:
other: Method A.11
Deviations:
not specified
GLP compliance:
no
Analytical monitoring:
no
Vehicle:
no
Test organisms (species):
other: Rainbow trout
Details on test organisms:
No details available
Limit test:
no
Total exposure duration:
48 h
Post exposure observation period:
None
Hardness:
No data available
Test temperature:
No data available
pH:
No data available
Dissolved oxygen:
No data available
Salinity:
Not applicable
Conductivity:
No data available
Nominal and measured concentrations:
No data available
Details on test conditions:
None
Reference substance (positive control):
no
Duration:
48 h
Dose descriptor:
other: TL0
Effect conc.:
> 1 000 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Key result
Duration:
48 h
Dose descriptor:
other: TL50
Effect conc.:
> 1 000 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Duration:
48 h
Dose descriptor:
other: TL100
Effect conc.:
> 1 000 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Details on results:
None
Results with reference substance (positive control):
No reference substance tested.
Reported statistics and error estimates:
None
Validity criteria fulfilled:
yes
Conclusions:
The TL50 of FAT 11127/B in this fish acute toxicity test was determined to be greater than 1000 mg/L.
Executive summary:

The acute fish toxicity test was performed using a methodology similar to OECD Guideline 203. Rainbow trout were used in this test. Based on the findings of the study, the following results were obtained:

TL0 >1000 mg/L

TL50 >1000 mg/L

TL100 >1000 mg/L.

Description of key information

A couple of studies investigating the toxicity of Direct Blue 094 to fish are available. The key acute fish toxicity test was performed using a method similar to OECD Guideline 203. Rainbow trouts were used in this test. Based on the findings of the study, TL50 was determined to be >1000 mg/L. The outcome of a supporting study conducted with similar methodology, also pointed to TL50 of Direct Blue 094 being >1000 mg/L. The TL50 of FAT 11127/A & FAT 1127/B in fish acute toxicity tests was determined to be greater than 1000 mg/L.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
1 000 mg/L

Additional information