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Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
Aug 3, 2015
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Qualifier:
according to
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
GLP compliance:
no
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Type:
log Pow
Partition coefficient:
7.04
Remarks on result:
other: temperature (assumed room temperature) and pH are not available

Results and discussion

The results are presented in the following table:

 

Rt

k

Log k

Log Po/w

 

(min)

 

 

 

 T0uracyl elsd

0.20

-

-

-

 Tetradecanoic acid

0.7949

2.975

0.473

6.11

 Hexadecanoic acid

1.3967

5.984

0.777

7.17

 Octadecanoic acid

2.574

11.870

1.074

8.23

 Eicosanoic acid

4.7734

22.867

1.359

9.29

 

 

 

 

 

 SP173 #K6J-08

1.288

5.44

0.736

7.04

Description of key information

log Pow =7.04

Key value for chemical safety assessment

Log Kow (Log Pow):
7.04
at the temperature of:
25 °C

Additional information

The partition coefficient of the substance trihexyl phosphate (CAS No. 2528-39-4) was determined according to OECD 117 (HPLC method).