Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
genetic toxicity in vivo, other

Data source

Reference
Reference Type:
other: Body responsible for the test
Title:
Unnamed

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)
Version / remarks:
Type of genotoxicity
chromosome aberration
GLP compliance:
yes
Type of assay:
other: Non-bacteriological test in vivo - 6th amendment data

Test animals

Species:
rat
Strain:
Wistar

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
aqua p.i.
No. of animals per sex per dose:
Male: 1200 mg/kg; No. of animals: ; Sacrifice time: hours

Results and discussion

Additional information on results:
Observations:
The treatment induced clinical symptoms; no cytotoxic
effects occured. The preparation point were 6 h, 24 h and 48 h after begin of the treatment.

Applicant's summary and conclusion

Conclusions:
Interpretation of results:
negative