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Boiling point

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Reference
Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From March 28th, 2018 to April 4th, 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
EU Method A.2 (Boiling Temperature)
Deviations:
no
Qualifier:
equivalent or similar to
Guideline:
OECD Guideline 103 (Boiling Point)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
method according to Siwoloboff
Key result
Atm. press.:
1 002.7 hPa
Decomp. temp.:
170 °C
Remarks on result:
not determinable
Atm. press.:
993.1 hPa
Decomp. temp.:
187 °C
Remarks on result:
not determinable

During the first test, at a temperature of about 170 °C darkening and clouding of the substance was observed. It was evident that the test item decomposed below the boiling point under atmospheric pressure of 1002.7 hPa at a temperature of about 170.0 °C. On the second test darkening was observed at 187ºC under atmospheric pressure of 993.1 hPa, at 250°C the colour of the sample was black and at about 262.5°C the substance was no longer transparent. On the second test it was determined that the test item decomposed before reaching boiling point at 187ºC. Visual observations were straitened due to very slow and gradual decomposition process of the substance – initial change of colour was difficult to notice. Due to the safety reasons it is recommended to acknowledge the lower initial decomposition temperature.

Table 1. The observed values of the initial decomposition temperature of the test item

Sample

Atmospheric pressure. hPa

The initial decomposition temperature. ºC

1

1002.7

170.0

2

993.1

187.0

Due to safety reasons the lower observed

initial decomposition temperature is acknowledged, ºC

~170.0

Conclusions:
The test item decomposed at 170 ± 0.2ºC at 1002.7 hPa before reaching boiling point.
Executive summary:

The boiling point of the test substance was determined according to EU A.2 Method (Method according to Siwoloboff), under GLP conditions. The preliminary test the temperature was increased at a rate of 10°C/min to determine approximate value of boiling point. Two final tests were performed. The first one was carried out at 120-400 °C temperature range with a heating rate of 3°C/min, . The second test was performed at 150-400 °C temperature range with a heating rate of 1 °C/min. It was concluded that the test item degrades before reaching boiling point. On the first test, degradation temperature was 170ºC at 1002.7 hPa while in the second one it was 187.0ºC at 9923.1 hPa. Due to safety reasons 170ºC was acknowledged as the initial decomposition temperature.

Description of key information

Key study. Method according to EU A.2, GLP study. The test item decomposed below boiling point at 170ºC (at 1002.7 hPa).

Key value for chemical safety assessment

Boiling point at 101 325 Pa:
170 °C

Additional information

The boiling point of the test substance was determined according to the OECD 103 Guideline and EU A.2 Method (Method according to Siwoloboff), under GLP conditions. The preliminary test the temperature was increased at a rate of 10°C/min to determine approximate value of boiling point. Two final tests were performed.T he first one was carried out at 120-400 °C temperature range with a heating rate of 3°C/min, . The second test was performed at 150-400 °C temperature range with a heating rate of 1 °C/min. It was concluded that the test item degrades before reaching boiling point. On the first test, degradation temperature was 170ºC at 1002.7 hPa while in the second one it was 187.0ºC at 9923.1 hPa. Due to safety reasons 170ºC was akcnowledged as the initial decomposition temperature.