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EC number: 823-920-1 | CAS number: 5341-95-7
Ready biodegradation: readily biodegradable by micro-organisms, fulfilling all criteria (OECD 301F): 85.8±0.9 degradation within 28 days
Simulation tests in surface water, sludge, soil and sediment: Data waiving
In the reliable key study, the test item 2,3 -butanediol((2R,3S)-rich) was investigated to determine the ready biodegradability over a period of 28 days in accordance with OECD Guidelines (Test No. 301 Ready Biodegradability, 301 F) and in compliance with GLP. The secondary effluent of a treatment plant (Jin-ju munsan public sewage treatment facility, Republic of Korea) was used as the inoculum. After collection, it was kept aerobic during transport and coarse particles were removed by settling for 1 hour.
The results were as follows: The percentage microbial degradation of the reference item was 87.5% at 14 days, thus confirming suitability of the inoculum. In toxicity control, the percentage microbial degradation was 76.1% at 14 days, thus it was confirmed that the test item had obviously no inhibitory effect on the activity of the inoculum. In test suspensions, the percentage microbial degradation of the test item was 84.5% at the end of the 10-d window (11.5 days) and was 85.8% at end of the test (28 days).
Therefore, 2,3-butanediol((2R,3S)-rich) was classified as readily degradable by micro-organisms in the aquatic environmental according to the pass level of biodegradability specified by the OECD 301F (1992).
Simulation tests in surface water, sludge, soil and sediment
In accordance with column 2 of REACH Annex IX, the studies do not need to be conducted if the substance is readily biodegradable. This is the case for the submission substance.
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