Registration Dossier
Registration Dossier
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EC number: 823-920-1 | CAS number: 5341-95-7
Endpoint summary
Administrative data
Description of key information
Hydrolysis: data waiving
Ready biodegradation: readily biodegradable by micro-organisms, fulfilling all criteria (OECD 301F): 85.8±0.9% degradation within 28 days
Adsorption / desorption: data waiving; estimated Koc: 1 L/kg // log Koc: -0.6584 (EPISuite KOCWIN v2.01)
Additional information
Stability - Hydrolysis
In accordance with column 2 of REACH Annex VIII, the study does not need to be conducted if the substance is readily biodegradable. This is the case for the submission substance. In general, abiotic degradation by hydrolysis of the submission substance is expected to be low as indicated by the dissociation constant (IUCLID section 4.21).
Ready biodegradation
In a reliable key study, the test item 2,3 -butanediol((2R,3S)-rich) was determined to be ready biodegradability over a period of 28 days. Percentage microbial degradation of the test item was 84.5% at the end of the 10-d window (11.5 days) and was 85.8% at end of the test (28 days). Therefore, the submission substance is expected to fast disappear in case of release and environmental exposure will be vegetable.
Transport and distribution - Adsorption / desorption
In accordance with column 2 of REACH Annexes VIII and IX, the study does not need to be conducted if based on the physicochemical properties the substance can be expected to have a low potential for adsorption (e.g. the substance has a low octanol water partition coefficient), or the substance and its relevant degradation products decompose rapidly. This is the case for the submission substance.
The estimated Koc is calculated at 1 L/kg or 0.5058 L/kg by the MCI or Kow method, respectively (EPISuite KOCWIN v2.01, exp. log Kow: -0.81). Based on the low log Kow and estimated Koc value, the submission substance is not expected to adsorb to soil and sediment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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