Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

sub-chronic toxicity: dermal
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
Justification for type of information:
N-[3-(dimethylamino)propyl] C6-9 alkyl amides was mildly irritating to skin but severely irritating to eyes, so any local effects would be limited to irritation. The ECHA Guidance document allows the calculation of dermal long term DNELs based on the oral NOAEL. This is conservative approach as dermal absorption can be expected to be less than by the oral route. No testing is justified which avoid unnecessary use of additional animals.

Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion