Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 701-199-3 | CAS number: -
Based on the available study, aluminium potassium fluoride does not induce sensory irritation in the respiratory tract.
The airway irritating properties of aluminium potassium fluoride were studied by exposing three groups of four male mice to test atmospheres containing the substance at concentrations of 283, 592 and 604 mg/m3 for a single period of 20, 20 and 30 minutes, respectively (TNO, 1999b).
A decrease in breathing rate or post-inspiratory apnoea were not seen in the breathing pattern. During exposure, no changes in behaviour were seen. No abnormalities or clinical signs were seen during the 7-day observation period. None of the mice died. Dose (exposure*time) related weight decrease was not observed. Abnormalities at necropsy consisted primarily of discoloured areas on the lungs to a varying extent in the highest concentration group.
From the results of the present study in mice, it was concluded that a sensory irritation response of inhalable particles of aluminium potassium fluoride at the technically highest attainable concentration under the conditions of this study (604 mg/m3) was not found.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Close Do not show this message again