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Physical & Chemical properties

Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
12 Feb - 13 Feb 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
not specified
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
not specified
GLP compliance:
no
Type of method:
effusion method: vapour pressure balance
Test no.:
#1
Temp.:
20 °C
Vapour pressure:
0 Pa
Test no.:
#2
Temp.:
25 °C
Vapour pressure:
0 Pa
Test no.:
#3
Temp.:
50 °C
Vapour pressure:
0.001 Pa

Individual Results

The vapour pressure was measured in the temperature range of 70 °C to 120 °C. According to sponsor's information the test item has several constituents. A molecular mass of 355.57 g/mol (C21H41NO3, stearoyl sarcosine, most abundant constituent) was used to calculate the vapour pressure according to the Hertz-Knudsen equation. The vapour pressures at the corresponding temperatures are listed in Table 1. After the measurement a mass loss of approx. 11 % (w/w) was determined of the starting sample weight (858.8 mg).

Table 1: Measured vapour pressures and corresponding temperatures

Temperature / °C

Vapour pressure / hPa

70

4.8 × 10-5

80

1.2 × 10-4

90

2.2 × 10-4

100

4.7 × 10-4

110

8.2 × 10-4

120

1.1 × 10-3

The vapour pressure values for 20, 25 and 50 °C are calculated, using the Antoine constants A, B and C as shown in Table 2.

Table 2: Antoine parameters and extrapolated vapour pressures

T / °C

p / hPa

log (p/hPa) = A + B/(C+T[°C])

20

7.1 × 10-7

A =

6.72748

25

1.2 × 10-6

B =

-3774.82

50

1.1 × 10-5

C =

273.15

Final Result

The following vapour pressure values for the test item were extrapolated from the experimental data (vapour pressure balance):

T / °C

p / hPa

p / Pa

20

7.1 × 10-7

7.1 × 10-5

25

1.2 × 10-6

1.2 × 10-4

50

1.1 × 10-5

1.1 × 10-3

Description of key information

7.1E-5 Pa at 20 ºC (OECD 104, effusion method).

1.2E-4 Pa at 25 ºC (OECD 104, effusion method).

0.0011 Pa at 50 ºC (OECD 104, effusion method).

Key value for chemical safety assessment

Vapour pressure:
0 Pa
at the temperature of:
20 °C

Additional information