Registration Dossier

Physical & Chemical properties

Particle size distribution (Granulometry)

Administrative data

Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
Jan - Mar 2019
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Cross-reference
Reason / purpose:
reference to other study
Reference
Endpoint:
relative density
Type of information:
experimental study
Adequacy of study:
key study
Study period:
Jan - March 2019
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
EU Method A.3 (Relative Density)
Version / remarks:
2016
Deviations:
no
Qualifier:
according to
Guideline:
OECD Guideline 109 (Density of Liquids and Solids)
Version / remarks:
2012
Deviations:
no
Qualifier:
according to
Guideline:
EPA OPPTS 830.7300 (Density / Relative Density / Bulk Density)
Version / remarks:
2002
Deviations:
no
GLP compliance:
yes
Type of method:
air comparison pycnometer (for solids)
Specific details on test material used for the study:
TREATMENT OF TEST MATERIAL PRIOR TO TESTING
The test item was reduced by grinding using a mortar and dried in a desiccator under vacuum using silica gel as the drying agent at 18.7 ± 0.2°C for 45 hours.
Dynamic viscosity of test material:
not applicable (substance is a solid)
Key result
Type:
relative density
Density:
1.42 other: dimensionless
Temp.:
20 °C
Remarks on result:
other: D 20 /4
Key result
Type:
density
Density:
1.42 g/cm³
Temp.:
20 °C

Experiment 1: 1.422 g/cm^3

Experiment 2: 1.423 g/cm^3

The individual measurements were obtained with an accuracy of < 0.02 g/cm^3.

Conclusions:
The relative density D20/4 of the substance was determined to be 1.42.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2019

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
ISO 13320 (Particle size analysis - Laser diffraction methods)
Version / remarks:
2009
Deviations:
no
Principles of method if other than guideline:
According to REACH Article 13(3) tests on substances shall be conducted in accordance with the test methods laid down in a Commission Regulation or in accordance with other international test methods recognised by the Commission or the Agency as being appropriate. No particle size distribution test method is laid down in regulation (EC) No 440/2008. OECD 110 TG ‘Particle Size Distribution/FibreLength and Diameter Distributions’ dates from 1981 and describes two methods in detail; both methods have restrictions and are not applicable to the entire size range. ECHA’s Guidance on information requirements and Chemical Safety Assessment-Chapter R.7a stipulates that many methods are available for particle size measurements but none of them is applicable to the entire size range.
The guidance mentions Laser scattering/diffraction as a method for particles of all kinds and makes reference to ISO 13320:2009.

According to Guidance document EUR 20268 (2002), the laser diffraction technique is applicable to particles of respirable and inhalable size. The MMAD can be calculated when the density is known.
GLP compliance:
yes
Type of method:
Laser scattering/diffraction
Type of particle tested:
primary particle
Type of distribution:
volumetric distribution

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: particulate/powder
Details on test material:
- Identification: Zirconium (IV) acetylacetonate (Zr-acac)
- Description: White to off-white powder
- Storage conditions: At room temperature
Specific details on test material used for the study:
Relative density: 1.42
The test item was tested as received.

Results and discussion

Mass median aerodynamic diameter:
2 598 µm
Particle sizeopen allclose all
Key result
Percentile:
D10
Mean:
1 310 µm
Remarks on result:
other: St.dev info not yet available
Key result
Percentile:
D50
Mean:
2 180 µm
Remarks on result:
other: St.dev info not yet available
Key result
Percentile:
D90
Mean:
3 010 µm
Remarks on result:
other: St.dev info not yet available
Particle size distribution at different passages
Size:
< 10 µm
Distribution:
0 %
Remarks on result:
other: volume of sample

Applicant's summary and conclusion

Conclusions:
The particle size distribution of the substance was determined as follows: D10 = 1310 μm, D50 = 2180 μm and D90 = 3010 μm.
There were no particles smaller than 10 μm detected in the tested sample volume.
The MMAD was calculated to be 2598 μm.