Registration Dossier

Environmental fate & pathways

Biodegradation in water: screening tests

Administrative data

Endpoint:
biodegradation in water: ready biodegradability
Type of information:
(Q)SAR
Adequacy of study:
key study
Study period:
December 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification

Data source

Reference
Reference Type:
other: QSAR prediction
Title:
PQSAR v1.1
Author:
ProtoQSAR
Year:
2018
Bibliographic source:
ProtoQSAR SL, CEEI Valencia, Parque Tecnológico de Valencia, Avda. Benjamin Franklin 12, Desp. 8, 46980 Paterna (Valencia), Tel. +34 960 88 06 58, E-mail. info@protoqsar.com

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I))
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Specific details on test material used for the study:
SMILES: CCOC(=O)CC(=O)OCC(=O)OCC

Results and discussion

% Degradation
Remarks on result:
readily biodegradable based on QSAR/QSPR prediction

Applicant's summary and conclusion

Interpretation of results:
readily biodegradable
Conclusions:
Readily biodegradable (predicted value using PQSAR model)
Executive summary:

Regulatory purpose: This study was designed to generate estimated in silico (nontesting) data for Biodegradation for 2-ethoxy-2-oxoethyl ethyl malonate to be used in the regulatory framework of REACH.

Results: Readily biodegradable (predicted value using PQSAR model)