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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Reference
Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
2006
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Data is from peer reviewed journal. Study conducted according a standardised method.
Reason / purpose:
reference to same study
Reason / purpose:
reference to same study
Qualifier:
according to
Guideline:
OECD Guideline 201 (Alga, Growth Inhibition Test)
Version / remarks:
Adopted 7 June 1984
GLP compliance:
not specified
Specific details on test material used for the study:
Composition of test material, percentage of components: Trihexyl(tetradecyl)phosphonium chloride (258864-54-9), >= 95%
Analytical monitoring:
yes
Details on sampling:
Chemical analysis of the test solution was carried out at the beginning and end of the test to ensure that organism exposure was consistent with that expected from nominal concentrations used.
Vehicle:
no
Test organisms (species):
Pseudokirchneriella subcapitata (previous names: Raphidocelis subcapitata, Selenastrum capricornutum)
Test type:
not specified
Water media type:
freshwater
Limit test:
no
Total exposure duration:
72 h
Hardness:
Not specified
Test temperature:
Not specified
pH:
Not specified
Dissolved oxygen:
Not specified
Salinity:
Not specified
Conductivity:
Not specified
Nominal and measured concentrations:
Not specified
Details on test conditions:
Algal cultures in exponential growth phase were exposed to various concentration of the test material for 72h at which point the growth of the culture was examined by electronic particle counting techniques.
Reference substance (positive control):
not specified
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
0.042 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
growth rate
Remarks on result:
other: 95% CI (mg/L): 0.037 - 0.048
Details on results:
Although the test duration was 72h, only the results at 48h are available in the publication.
Note that for this test material, the end-point chemical analysis showed that the final concentration in the medium was less than 10% of the initial nominal concentration.
Results with reference substance (positive control):
Some common solvents were tested concurrently and the results are similar to those available previously.
Validity criteria fulfilled:
not specified
Conclusions:
The acute toxicity of Trihexyltetradecylphosphonium chloride to Pseudokirchneriella subcapitata was investigated in accordance with OECD guideline 201. The 48-h EC50 was 0.042 mg/L.
Executive summary:

In this study, the acute toxicity of the test substance (Trihexyltetradecylphosphonium chloride) to Pseudokirchneriella subcapitata was determined in a 48 hour test according to the OECD Guideline No. 201 (1984). Under the conditions of this study, a 48h EC50 of 0.042 mg/L was obtained.

Description of key information

In this study, the acute toxicity of the test substance (Trihexyltetradecylphosphonium chloride) to Pseudokirchneriella subcapitata was determined in a 48 hour test according to the OECD Guideline No. 201 (1984). Under the conditions of this study, a 48h EC50 of 0.042 mg/L was obtained.

Key value for chemical safety assessment

EC50 for freshwater algae:
0.042 mg/L

Additional information