Carbendazim

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:

short-term toxicity to aquatic invertebrates

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Data source

Reference

Reference Type:

publication

Title:

Unnamed

Year:

2009

Report date:

2009

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)

GLP compliance:

yes

Test material

Test material information

Constituent 1

Reference substance name:

Carbendazim

EC Number:

234-232-0

EC Name:

Carbendazim

Cas Number:

10605-21-7

Molecular formula:

C9H9N3O2

IUPAC Name:

carbendazim

Specific details on test material used for the study:

Purity 99.4%, solid, white crystalline powder.

Sampling and analysis

Analytical monitoring:

yes

Test solutions

Vehicle:

yes

Details on test solutions:

2.5 mg/l of Carbendazim in DMF.

Test organisms

Test organisms (species):

Daphnia magna

Details on test organisms:

2 x 10 daphniids per tested concentration (6 x 10 in the range 0.001 to 10 mg/l) and control.
Age: max 24 h old.
Photoperiod 16 h light

Study design

Test type:

static

Water media type:

freshwater

Total exposure duration:

48 h

Test conditions

Test temperature:

20°C

Nominal and measured concentrations:

25 concentrations between 0.0010 mg/l and 1000 mg/l

Results and discussion

Effect concentrations

Duration:

48 h

Dose descriptor:

EC50

Effect conc.:

0.15 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mobility

Applicant's summary and conclusion

Validity criteria fulfilled:

yes

Conclusions:

The daphnia magna EC50 immobilisation (48 h) was 0.15 mg/l (95% confidence interval: 0.10 - 0.18 mg/l).