Registration Dossier
Registration Dossier
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EC number: 204-524-2 | CAS number: 122-14-5
Endpoint summary
Administrative data
Description of key information
The following studies are available for fenitrothion:
Relevant studies and endpoints |
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Hydrolysis |
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Relevant study |
Endpoints |
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5.1.2,Key Study, Takarazuka Research Center, 1988, (HM-080-0094) Hydrolysis of Fenitrothion in Water as a Function of pH at 25°C |
DT50 Half-life at 25°C 191-200days at pH5 180-186days at pH7 100-101days at pH9 |
Hydrolysis rate constant at 25°C 3.46 - 3.63 day-1 at pH5 3.73 - 3.85 day-1 at pH7 6.88 - 6.96 day-1 at pH9 |
5.1.2 Supporting Study, Laboratry of Biochemistry and Toxicology Takarazuka Research Center , 1981, (HW-10-0212) Hydrolysis in Water |
DT50 Half-life at pH7: 200-630days at 15°C 17-61days at 30°C 4-8days at 45°C |
Hydrolysis rate constant 1.5x108sec-1at 15°C 1.4x107sec-1at 30°C 1.1x108sec-1at 45°C |
Additional information
5.1.2,Key Study, Takarazuka Research Center, 1988, (HM-080-0094)
Degradation products as well as fenitrothion were tentatively identified by two-dimensional thin-layer co-chromatography with authentic standards and their chemical identities were confirmed by high-performance liquid chromatography.
1. demethylated fenitrothion (DM-SMT)
(dominant degradation product at pH5 and pH7)
2. 3-methyl-4 -nitrophenol (NMC)
(dominant degradation product at pH9)
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