N,N''-(methylenedi-4,1-phenylene)bis[N'-(4-methylphenyl)urea]

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From 02 February 1994 to 11 February 1994

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Reason / purpose for cross-reference:

other: Reference to the validated analytical method used for quantification of the water samples.

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Version / remarks:

1992

Deviations:

no

GLP compliance:

yes

Type of method:

column elution method

Key result

Water solubility:

< 9 µg/L

Temp.:

20 °C

pH:

6

Remarks on result:

other: The concentration in the water samples obtained from two test columns and the blank column was below the limit of detection.

Conclusions:

The water solubility of the substance at 20°C was determined to be < 9 µg/L.

Executive summary:

The water solubility of the substance was determined using the column elution method in a GLP study according to EC A.6. Quantification was performed by HPLC-UV. The substance concentration was below the limit of detection. The water solubility at 20°C was therefore determined to be < 9 µg/L. The pH of the aqueous samples was 6.

Description of key information

Water solubility at 20°C: < 9 µg/L (EC A.6: Column elution method) 

Key value for chemical safety assessment

Water solubility:

9 µg/L

at the temperature of:

20 °C

Additional information

The substance concentration in the water samples was below the limit of detection.