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Environmental fate & pathways

Biodegradation in water: screening tests

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Reference
Endpoint:
biodegradation in water: ready biodegradability
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Justification for type of information:
Please refer to the attached analogue justification provided in IUCLID Section 13.
Reason / purpose for cross-reference:
read-across source
Reason / purpose for cross-reference:
read-across source
Reason / purpose for cross-reference:
read-across source
Parameter:
% degradation (CO2 evolution)
Value:
82
Sampling time:
28 d
Remarks on result:
other: Source: CAS 68583-51-7, Key
Parameter:
% degradation (CO2 evolution)
Value:
104.5
Sampling time:
28 d
Remarks on result:
other: 95% CL: 99.9 - 109.2%
Remarks:
Source: CAS 68583-51-7, Sup. 1
Parameter:
% degradation (CO2 evolution)
Value:
107.6
Sampling time:
28 d
Remarks on result:
other: 95% CL: 99.1 - 116.1%
Remarks:
Source: CAS 68583-51-7, Sup. 2
Details on results:
In all studies with the source substance more than 60% degradation was recorded within the 10-day time window. Therefore, the test substance is regarded as readily biodegradable.
Interpretation of results:
readily biodegradable

Description of key information

Readily biodegradable (82 – 100 % degradation after 28 d) based on read across from CAS 68583-51-7

Key value for chemical safety assessment

Biodegradation in water:
readily biodegradable

Additional information

There is no study available, in which the biodegradation of propylene dinonanoate (CAS 41395-83-9) was tested. Therefore, read-across to the structurally related source substance decanoic acid, mixed diesters with octanoic acid and propylene glycol (CAS 68583-51-7) was performed in accordance with Regulation (EC) No 1907/2006 Annex XI, 1.5. The source substance is characterized by similar fatty acid chain lengths as well as alcohol component and is therefore considered suitable representative for the assessment of the biodegradability of the target substance. A detailed read-across justification is provided in the analogue justification attached in IUCLID section 13.

Three studies are available evaluating the ready biodegradability of the source substance decanoic acid, mixed diesters with octanoic acid and propylene glycol (CAS 68583-51-7).

The key study was conducted according to the EU Method C.4-C (GLP) under aerobic conditions using domestic activated sludge as inoculum. A mean biodegradation of 82% was observed after 28 d. The substance reached the pass level biodegradation of > 60% within the 10-day window and is therefore considered readily biodegradable.

This result is supported by two GLP-Guideline studies with the same source substance decanoic acid, mixed diesters with octanoic acid and propylene glycol according to OECD 301B using secondary effluent from an activated-sludge plant as inoculum. A mean biodegradation of 104.5 and 107.6%, respectively, and the fulfilment of the 10-day window criterion classify the source substance as readily biodegradable.

On the basis of the read across data, the target substance propylene dinonanoate (CAS 41395-83-9) is considered readily biodegradable.

[Type of water: freshwater]