Registration Dossier
Registration Dossier
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EC number: 221-361-2 | CAS number: 3077-27-8
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to same study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- flask method
- Water solubility:
- 5.9 mg/L
- Temp.:
- 25 °C
- pH:
- 5
Reference
The calibration equation resulted as:
y = 199.372889 x + 0.026495
R² = 0.999946
Sample |
Measured water solubility [µg/mL] |
Sample #1 |
5.2 |
Sample #2 |
1.5 |
Sample #3 |
6.6 |
Assuming sample 2 as an outlier, the averaged solubility of of the test item in water at pH 5 is 5.9 μg/mL.
No evidence for an instability of the substance in water was determined.
Description of key information
Water solubility = 5.9 mg/L at 25 °C, pH 5 (OECD Guideline 105, flask method)
Key value for chemical safety assessment
- Water solubility:
- 5.9 mg/L
- at the temperature of:
- 25 °C
Additional information
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