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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Reason / purpose:
reference to same study
Reason / purpose:
reference to same study
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
GLP compliance:
no
Type of method:
flask method
Water solubility:
5.9 mg/L
Temp.:
25 °C
pH:
5

The calibration equation resulted as:

y = 199.372889 x + 0.026495

R² = 0.999946

Sample

Measured water solubility [µg/mL]

Sample #1

5.2

Sample #2

1.5

Sample #3

6.6

Assuming sample 2 as an outlier, the averaged solubility of of the test item in water at pH 5 is 5.9 μg/mL.

No evidence for an instability of the substance in water was determined.

Description of key information

Water solubility = 5.9 mg/L at 25 °C, pH 5 (OECD Guideline 105, flask method)

Key value for chemical safety assessment

Water solubility:
5.9 mg/L
at the temperature of:
25 °C

Additional information