Registration Dossier
Registration Dossier
Diss Factsheets
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EC number: 201-145-4 | CAS number: 78-81-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Guidance on Safe Use
Administrative data
First-aid measures
General advice
Remove contaminated, soaked clothing immediately and dispose of safely. First aider needs to protect himself.
Inhalation
Keep at rest. Aerate with fresh air. Call a physician immediately. Symptoms of poisoning may develop many hours
after exposure.
Eyes
Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Remove contact lenses.
Immediate medical attention is required.
Skin
Wash off with 3% acetic acid followed by large amounts of plain water for at least 5 min as a final step. Immediate
medical treatment is necessary as untreated wounds from corrosion of the skin heal slowly and with difficulty.
Ingestion
Call a physician immediately. Do not induce vomiting without medical advice.
Fire-fighting measures
Suitable extinguishing media
alcohol-resistant foam, dry chemical, carbon dioxide (CO2), water spray
Extinguishing media which must not be used for safety reasons
Do not use a solid water stream as it may scatter and spread fire.
Special exposure hazards arising from the substance or preparation itself, its combustion products, or
released gases
Under conditions giving incomplete combustion, hazardous gases produced may consist of:
carbon monoxide (CO)
carbon dioxide (CO2)
nitrogen oxides (NOx)
Combustion gases of organic materials must in principle be graded as inhalation poisons
Vapour is heavier than air and can travel considerable distance to a source of ignition and flashback
Vapours may form explosive mixtures with air
Special protective equipment for fire-fighters
Fire fighter protection should include a self-contained breathing apparatus (NIOSH-approved or EN 133) and full
fire-fighting turn out gear.
Precautions for fire-fighting
Cool containers / tanks with water spray. Water run-off and vapor cloud may be corrosive. Dike and collect water
used to fight fire. Keep people away from and upwind of fire.***
Accidental release measures
Personal precautions
Avoid contact with skin and eyes. Avoid breathing vapors or mists. Keep people away from and upwind of
spill/leak. Ensure adequate ventilation, especially in confined areas. Keep away from heat and sources of ignition.
Environmental precautions
Prevent further leakage or spillage. Do not discharge product into the aquatic environment without pretreatment
(biological treatment plant).
Methods for containment
Stop the flow of material, if possible without risk. Dike spilled material, where this is possible.
Methods for cleaning up
Soak up with inert absorbent material. DO NOT use combustible materials such as sawdust. Keep in suitable,
closed containers for disposal. If liquid has been spilt in large quantities clean up promptly by scoop or vacuum.
Dispose of in accordance with local regulations. Take necessary action to avoid static electricity discharge (which
might cause ignition of organic vapours).
Handling and storage
Advice on safe handling
Avoid contact with skin, eyes and clothing. Do not use compressed air for filling, discharging or handling. Wash
hands before breaks and immediately after handling the product. Provide sufficient air exchange and/or exhaust in
work rooms. Refill and handle product only in closed system.
Advice on protection against fire and explosion
Keep away from sources of ignition - No smoking. Take necessary action to avoid static electricity discharge
(which might cause ignition of organic vapours). In case of fire, emergency cooling with water spray should be
available. Ground and bond containers when transferring material. Vapour is heavier than air and can travel
considerable distance to a source of ignition and flashback. Vapours may form explosive mixture with air.
Technical measures/Storage conditions
Keep containers tightly closed in a cool, well-ventilated place. Handle and open container with care. Handle under
nitrogen, protect from moisture.
Suitable material
stainless steel, mild steel, aluminium
Advice on common storage
Incompatible products:
strong acids
oxidizing agents
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- UN 1214
Shipping information
- Proper shipping name and description:
- Isobutylamine
SpecialProvisionsopen allclose all
Inland waterway transport (UN RTDG/ADN(R))
- UN number:
- UN 1214
Shippingopen allclose all
Remarksopen allclose all
Marine transport (UN RTDG/IMDG)
- UN number:
- UN 1214
Shipping information
- Proper shipping name and description:
- Isobutylamine
Remarksopen allclose all
Air transport (UN RTDG/ICAO/IATA)
- UN number:
- UN 1214
Shipping information
- Proper shipping name and description:
- Isobutylamine
Remarksopen allclose all
SpecialProvisionsopen allclose all
Exposure controls / personal protection
Stability and reactivity
Disposal considerations
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
