Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

The acute oral LD50of 2-(N-ethylanilino) ethanol in Wistar rats is > 2000 mg/kg body weight.

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed
Dose descriptor:
discriminating dose
2 000 mg/kg bw

Acute toxicity: via inhalation route

Endpoint conclusion
Endpoint conclusion:
no study available

Acute toxicity: via dermal route

Endpoint conclusion
Endpoint conclusion:
no study available

Additional information

Since no mortality or any visible sub-lethal effects occurred in six animals tested, there is no reason to expect significant mortality between 2000 and 5000 mg/kg body weight.

Justification for classification or non-classification

According to CLP, the substance is not classified since the LD50 is > 2000 mg/kg bw.

According to the Globally Harmonized System of Classification and Labelling of Chemicals (GHS 2017):  Category 5 or Unclassified.

For reasons of animal welfare concern, testing of animals in GHS Category 5 ranges (2000-5000 mg/kg) is discouraged and should only be considered when there is a strong likelihood that results of such a test have a direct relevance for protecting human or animal health or the environment.