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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
4 October 2017 to 12 January 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
EU Method A.6 (Water Solubility)
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
Qualifier:
according to
Guideline:
EPA OPPTS 830.7840 (Water Solubility)
GLP compliance:
yes (incl. certificate)
Type of method:
flask method
Specific details on test material used for the study:
SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: Sponsor and ZMG-197685
- Expiration date of the lot/batch: 09 December 2017
- Purity test date: 28 December 2016
Key result
Water solubility:
117 g/L
Conc. based on:
test mat.
Temp.:
20 °C
Remarks on result:
other: mean value of the 24-, 48- and 72-hour measurments
Water solubility:
114 g/L
Conc. based on:
test mat.
Incubation duration:
24 h
Temp.:
20 °C
pH:
4.8
Water solubility:
119 g/L
Conc. based on:
test mat.
Incubation duration:
48 h
Temp.:
20 °C
pH:
4.4
Water solubility:
117 g/L
Conc. based on:
test mat.
Incubation duration:
72 h
Temp.:
20 °C
pH:
4.6
Details on results:
The maximum difference of the concentrations determined in the 24, 48 and 72 hour test samples was ≤ 15%. Based on this, the water solubility of the test item is given as the mean value of the analyzed concentrations.

Preliminary test

The content of test item dissolved in the water sample was 66.0 g/L.

Main study

The results for the samples taken at 24, 48 and 72 hours are given inTable 6.

The maximum difference of the concentrations determined in the 24, 48 and 72 hour test samples was≤ 15%. Based on this, the water solubility of the test item is given as the mean value of the analyzed concentrations.

No test item was detected in the pretreated sample from the blank water mixture.

Stirring time [hours]  Analyzed concentration [g/L] pH 
 24  114  4.8
 48  119  4.4
 72  117  4.6
Conclusions:
The flask method was applied for the determination of the water solubility of 1,3-dichloro-2-propanol.
The water solubility of the test item at 20°C was 117 g/L.
The pH of the aqueous samples was 4.4 – 4.8.

Description of key information

The flask method was applied for the determination of the water solubility of 1,3-dichloro-2-propanol.

The water solubility of the test item at 20°C was 117 g/L.

The pH of the aqueous samples was 4.4 – 4.8.

Key value for chemical safety assessment

Water solubility:
117 g/L
at the temperature of:
20 °C

Additional information