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Physical & Chemical properties

Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
18 Oct 2017 to 01 Nov 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
effusion method: isothermal thermogravimetry
Specific details on test material used for the study:
SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: Sponsor and ZMG-197685
- Expiration date of the lot/batch: 09 December 2017
- Purity test date: 28 December 2016
Key result
Test no.:
#1
Temp.:
20 °C
Vapour pressure:
150 Pa
Key result
Test no.:
#2
Temp.:
20 °C
Vapour pressure:
1.1 mm Hg
Key result
Test no.:
#3
Temp.:
25 °C
Vapour pressure:
250 Pa
Key result
Test no.:
#4
Temp.:
25 °C
Vapour pressure:
1.9 mm Hg

The results of the isothermal TGA analysis for the test item and the vapour pressure at 20°Cand 25°Care given in Table 3 and Table 4.

                     

  Table 3          
Results of the Vapour pressure Isothermal TGA Analysis

Temperature
[°C]

Weight loss
[µg/min]

νT
[g/cm2/h]

logνT

logPT

PT
[Pa]

30

87.0626

1.04x10-2

-1.98

2.60

4.0x102

 

87.8544

1.05x10-2

-1.98

2.60

4.0x102

40

189.983

2.27x10-2

-1.64

3.03

1.1x103

 

171.475

2.05x10-2

-1.69

2.98

9.4x102

50

365.535

4.36x10-2

-1.36

3.40

2.5x103

 

327.266

3.91x10-2

-1.41

3.33

2.2x103

 

Table 4          
Vapour Pressure of the Test Item

Temperature
[°C]

logPT

PT
[Pa]

PT
[mm Hg]

20

2.18

1.5x102

1.1

25

2.40

2.5x102

1.9

Conclusions:
The isothermal TGA effusion method was applied for the determination of the vapour pressure of 1,3-dichloro-2-propanol.
The vapour pressure of the test item at 20°C (293K) was 150 Pa (1.1 mmHg) and at 25°C (298K) was 250 Pa (1.9 mmHg).

Description of key information

The isothermal TGA effusion method was applied for the determination of the vapour pressure of 1,3-dichloro-2-propanol.

The vapour pressure of the test item at 20°C (293K) was 150 Pa (1.1 mmHg) and at 25°C (298K) was 250 Pa (1.9 mmHg).

Key value for chemical safety assessment

Vapour pressure:
150 Pa
at the temperature of:
20 °C

Additional information