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EC number: 949-084-9 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- fish early-life stage toxicity
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Initial mortality and vigour test of 28 days
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Justification for type of information:
- This report is part of wider research, including a reproductive toxicity test on fish.
A preliminary assessment was made at 28 days, stating with week-old fry - Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 210 (Fish, Early-Life Stage Toxicity Test)
- Principles of method if other than guideline:
- One week old fry were exosed to different concentrations of vanadium for 28 days.
Low-dose groups were maintained for longer periods up to maturity and reproduction effects examined. - GLP compliance:
- no
- Specific details on test material used for the study:
- Source of vanadium is described as predominantly sulphate, but oxy-sulphates and other salts will exist in the water column tested.
Results are expressed as vanadium.
Different valencies will also exist depending on pH
The report makes it clear that the vanadium form will be difficult to monitor and will change under conditions of analysis.
It is assumed that the vanadium under the test conditions would be penta-valent at the pH of the assessment - Analytical monitoring:
- yes
- Details on sampling:
- Assessment for vanadium content
- Vehicle:
- no
- Test organisms (species):
- Jordanella floridae
- Details on test organisms:
- Common name 'Flagfish', chosen for short life cycle
- Test type:
- flow-through
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 28 d
- Remarks on exposure duration:
- Lower dose treatment groups had extended exposure period of about 100 days to examine long-term effects including reproduction
- Hardness:
- Average 347 mg/l CaCO3
- Test temperature:
- Average 25 C
- pH:
- Average 8.15
- Dissolved oxygen:
- Average 7.4 mg/l
- Nominal and measured concentrations:
- 0.051, 0.58, 3.4, and 6.3 mg/l of vanadium, nominal
(Measured 0, 0.051, 0.58, 3.4, and 6.3 mg/l) - Reference substance (positive control):
- no
- Duration:
- 28 d
- Dose descriptor:
- LC10
- Effect conc.:
- > 0.56 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- element
- Remarks:
- Vanadium
- Basis for effect:
- mortality
- Key result
- Duration:
- 28 d
- Dose descriptor:
- LC10
- Effect conc.:
- > 1.9 mg/L
- Nominal / measured:
- estimated
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Remarks on result:
- other:
- Remarks:
- Starting with LC10 of 0.56 for V and using molecular weight of constituent with greatest proportion of vanadium
- Details on results:
- There was 100% mortality at 5.6 mg/l vanadium and > 50% mortality at 3.14 mg/l.
The lower concentrations of 0, 0.056 and 5.6 had a level of 5 - 10% mortality, including 4/60 deaths in the control. - Conclusions:
- It is concluded that the oxysuphate salts will be toxic at over 2 mg/l (0.56 mg/l vanadium).
Longer term exposure of 70 days showed good survival at 0.48 mg/l vanadiaum suggesting that there is no accumulative toxicity.
There was good survival, good egg production and good viablity of fry at 0.48 mg/l in the reproduction group extended to over 90 days exposure.
Reference
Description of key information
It is concluded that the oxysulphate salts will be toxic at over 2 mg/l (0.56 mg/l vanadium) and as vanadium is an essential element at low concentrations, it is not considered accumulative, suggesting that classification is not required
Longer term exposure of 70 days showed good survival at 0.48 mg/l vanadiaum suggesting that there is no accumulative toxicity.
There was good survival, good egg production and good viablity of fry at 0.48 mg/l in the reproduction group extended to over 90 days exposure.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 2 mg/L
Additional information
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