S-ethyl N-cyclohexylthiocarbamate

Toxicity to aquatic algae and cyanobacteria

Link to relevant study record(s)

Reference

Endpoint:

toxicity to aquatic algae and cyanobacteria

Type of information:

(Q)SAR

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification

Remarks:

QSAR

Justification for type of information:

The acute aquatic toxicity on algae QSAR prediction was assessed as adequate for regulatory purposes (Klimisch 2 study - result derived from a valid QSAR model and falling
into its applicability domain, with adequate and reliable documentation/justification).

Qualifier:

no guideline followed

Principles of method if other than guideline:

QSAR

GLP compliance:

no

Key result

Duration:

96 h

Dose descriptor:

EC50

Effect conc.:

ca. 0.19 mg/L

Nominal / measured:

estimated

Conc. based on:

test mat.

Remarks:

QSAR

Basis for effect:

not specified

Remarks:

QSAR

Details on results:

See it in the attachement.

Validity criteria fulfilled:

yes

Conclusions:

QSAR Prediction Acute EC50 (algae) equal to 0.19 mg/L, based on Thiocarbamates, Mono excess toxicity class model.The model is based on experimental
data measured in standard test species (e.g. Desmodesmus subspicatus or Pseudokirchneriella subcapitata), but it is intended to assess toxicity to the general trophic level that these species represent, i.e. aquatic plants.

Executive summary:

QSAR Prediction Acute EC50 (algae) equal to 0.19 mg/L

It is classifed as H400 (aquatic acute category 1) and H 410 ( aquatic chronic category 1)

Key value for chemical safety assessment

EC50 for freshwater algae:

0.19 mg/L