Registration Dossier

Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
from 20 March 2018 to 24 April 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report Date:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
EU Method A.4 (Vapour Pressure)
Version / remarks:
2016
Deviations:
no
Qualifier:
according to
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
2006
Deviations:
no
Qualifier:
according to
Guideline:
EPA OPPTS 830.7950 (Vapor Pressure)
Version / remarks:
1996
Deviations:
no
GLP compliance:
yes
Type of method:
effusion method: isothermal thermogravimetry

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
liquid
Details on test material:
Appearance: Clear colourless to pale yellow liquid
Storage: In refrigerator (2-8°C)

Results and discussion

Vapour pressureopen allclose all
Key result
Temp.:
20 °C
Vapour pressure:
1.5 Pa
Key result
Temp.:
25 °C
Vapour pressure:
2.7 Pa

Any other information on results incl. tables

Table: Results of the isothermal TGA analysis (test item)

Temperature
[°C]

Weight loss
[µg/min]

v(T)
[g/cm2/h]

log v(T)

log P(T)

P(T)
[Pa]

40

6.19921

7.40E-4

-3.13

1.13

1.3E1

 

5.96744

7.12E-4

-3.15

1.11

1.3E1

50

13.8703

1.66E-3

-2.78

1.58

3.8E1

 

13.4817

1.61E-3

-2.79

1.56

3.6E1

60

25.8640

3.09E-3

-2.51

1.92

8.4E1

 

25.4903

3.04E-3

-2.52

1.92

8.2E1

70

56.2312

6.71E-3

-2.17

2.36

2.3E2

 

54.7436

6.53E-3

-2.18

2.34

2.2E2

Applicant's summary and conclusion

Conclusions:
The vapour pressure of the substance at 20°C and 25°C was determined to be 1.5 Pa and 2.7 Pa, resp.
Executive summary:

The vapour pressure of the substance was determined using the isothermal thermogravimetric effusion method in a GLP study according to EC A.4, OECD 104 and OPPTS 830.7950.

The constants specific for the experimental arrangement were determined using a set of 5 reference substances. A vapour pressure curve for the test item was constructed from duplicate measurements at 40°C, 50°C, 60°C and 70°C (r = 0.998, n = 8).

The vapour pressure of the substance at 20°C and 25°C was calculated by extrapolation of the curve to be 1.5 Pa and 2.7 Pa, resp.