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Physical & Chemical properties

Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
from 2018-06-28 to 2019-02-05
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Version / remarks:
2004
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.8 (Partition Coefficient - HPLC Method)
Version / remarks:
2016
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Analytical method:
high-performance liquid chromatography
Key result
Type:
log Pow
Partition coefficient:
2.28
Temp.:
20 °C
Remarks on result:
other: pH was not determined
Details on results:
The partition coefficient at 20 °C of the test item was determined to be: log Pow = 2.28 ± < 0.01
Conclusions:
The test item has a partition coefficient at 20 °C of log Pow= 2.28 ± < 0.01.
Executive summary:

The partition coefficient at 20 °C of the test item was determined by means of the HPLC method according to Regulation EC No 440/2008 method A.8. and OECD 117 (2004) to be: log Pow = 2.28 ± < 0.01

Description of key information

The partition coefficient of the substance was determined to be 2.28 at 20 °C.

Key value for chemical safety assessment

Log Kow (Log Pow):
2.28
at the temperature of:
20 °C

Additional information

In order to determine the partition coefficient of the substance a key study was performed. According to Regulation EC No. 440/2008 method A.8., Regulation EC No 2016/266 method A.24. and OECD 117 (2004) the test item has a partition coefficient of log Pow= 2.28 ± < 0.01 at 20 °C.