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EC number: 259-130-3 | CAS number: 54380-33-5
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- from 2018-06-28- to 2019-02-07
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- Version / remarks:
- 1995
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.1 (Melting / Freezing Temperature)
- Version / remarks:
- 2008
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- differential scanning calorimetry
- Key result
- Melting / freezing pt.:
- > -40.6 - < -38.7 °C
- Atm. press.:
- 1 005 hPa
- Conclusions:
- The test item has a melting range of -38.7 to -40.6 °C at atmospheric pressure (1005 hPa).
- Executive summary:
A study was performed in accordance with OECD 102 (1995) in order to determine the melting point of the test item. A melting range of -38.7 to -40.6 °C at atmospheric pressure (1005 hPa) was determined by differential scanning calorimetry according to Regulation EC No 440/2008 Method A.1. and OECD Test Guideline 102 (1995).
Reference
Table 1: Results of the DSC-measurements
No. |
Sample weight / mg |
Onset of Effect / °C |
Range of effect l"C |
Weight loss / mg |
Atmospheric pressure / hPa |
|
1 |
20.65 |
-40.58 282.89 |
-50 to -30 (endo) 270-410 (endo) |
19.73 (96 %) |
1004.6 |
|
2 |
28.27 |
-38.69 288.37 |
-40 to -30 (endo) 270-410 (endo) |
27.88 (99 %) |
1004.6 |
During the heating phase a small endothermic effect was observed in the temperature range of -50 to -30 °C, which can't clearly be assigned to the melting of the test item.
Therefore, the melting of the test item was visually inspected in a test tube. This measurement showed a melting of the test item at -23 °C. Due to the fact that the DSC-measurements are more exact than the visual inspection, The DSC-measurements are used for the final result.
As the onset temperatures in both DSC-measurements tests deviate by more than 0.5 K from their mean value of 39.64 °C, a melting range can be stated. The test item has a melting range of -38.7 to -40.6 °C.
Description of key information
A melting range of -38.7 to -40.6 °C at atmospheric pressure (1005 hPa) was determined.
Key value for chemical safety assessment
- Melting / freezing point at 101 325 Pa:
- -40.6 °C
Additional information
A key study was performed in order to determine the melting point of the test substance. A melting range of -38.7 to -40.6 °C at atmospheric pressure (1005 hPa) was determined by differential scanning calorimetry according to Regulation EC No 440/2008 Method A.1. and OECD 102 (1995).
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