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Physical & Chemical properties

Melting point / freezing point

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Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
from 2018-06-28- to 2019-02-07
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Version / remarks:
1995
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Version / remarks:
2008
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
differential scanning calorimetry
Key result
Melting / freezing pt.:
> -40.6 - < -38.7 °C
Atm. press.:
1 005 hPa

Table 1: Results of the DSC-measurements

No.

Sample weight / mg

Onset of Effect / °C

Range of effect

l"C

Weight loss / mg

Atmospheric pressure / hPa

1

20.65

-40.58 282.89

-50 to -30 (endo) 270-410 (endo)

19.73 (96 %)

1004.6

2

28.27

-38.69 288.37

-40 to -30 (endo) 270-410 (endo)

27.88 (99 %)

1004.6

 

 

During the heating phase a small endothermic effect was observed in the temperature range of -50 to -30 °C, which can't clearly be assigned to the melting of the test item.

Therefore, the melting of the test item was visually inspected in a test tube. This measurement showed a melting of the test item at -23 °C. Due to the fact that the DSC-measurements are more exact than the visual inspection, The DSC-measurements are used for the final result.

As the onset temperatures in both DSC-measurements tests deviate by more than 0.5 K from their mean value of 39.64 °C, a melting range can be stated. The test item has a melting range of -38.7 to -40.6 °C.

Conclusions:
The test item has a melting range of -38.7 to -40.6 °C at atmospheric pressure (1005 hPa).
Executive summary:

A study was performed in accordance with OECD 102 (1995) in order to determine the melting point of the test item. A melting range of -38.7 to -40.6 °C at atmospheric pressure (1005 hPa) was determined by differential scanning calorimetry according to Regulation EC No 440/2008 Method A.1. and OECD Test Guideline 102 (1995).

Description of key information

A melting range of -38.7 to -40.6 °C at atmospheric pressure (1005 hPa) was determined.

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:
-40.6 °C

Additional information

A key study was performed in order to determine the melting point of the test substance. A melting range of -38.7 to -40.6 °C at atmospheric pressure (1005 hPa) was determined by differential scanning calorimetry according to Regulation EC No 440/2008 Method A.1. and OECD 102 (1995).