2-[(2-Acetamido-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]-1,3-propanediyl bis(4-methoxybenzoate)

Guidance on Safe Use

First-aid measures

- 4.1 Description of first aid measures

- General information

Instantly remove any clothing soiled by the product.

Symptoms of poisoning may even occur after several hours; therefore medical observation for at least 48

hours after the accident.

In case of irregular breathing or respiratory arrest provide artificial respiration.

Personal protection for the First Aider.

- After inhalation

Supply fresh air or oxygen; call for doctor.

Use a respiration bag or breathing device.

In case of unconsciousness bring patient into stable side position for transport.

- After skin contact

Instantly wash with water and soap and rinse thoroughly.

If skin irritation continues, consult a doctor.

- After eye contact Rinse opened eye for several minutes (10 - 15) under running water. Then consult doctor.

- After swallowing Do not induce vomiting; instantly call for medical help.

- 4.2 Most important symptoms and effects, both acute and delayed No further relevant information available.

- 4.3 Indication of any immediate medical attention and special treatment needed

No further relevant information available.

Fire-fighting measures

- 5.1 Extinguishing media

- Suitable extinguishing agents

CO2, extinguishing powder or water jet. Fight larger fires with water jet or alcohol-resistant foam.

- For safety reasons unsuitable extinguishing agents Do not use a heavy water stream.

- 5.2 Special hazards arising from the substance or mixture

Formation of toxic gases is possible during heating or in case of fire.

- 5.3 Advice for firefighters

- Protective equipment:

Wear self-contained breathing apparatus.

Do not inhale explosion gases or combustion gases.

Wear full protective suit.

- Additional information

Dispose of fire debris and contaminated fire fighting water in accordance with official regulations.

Accidental release measures

- 6.1 Personal precautions, protective equipment and emergency procedures

Wear protective equipment (described in section 8). Keep unprotected persons away.

Avoid causing dust.

Avoid contact with substance.

Do not inhale dust.

- 6.2 Environmental precautions: Do not allow product to reach sewage system or water bodies.

- 6.3 Methods and material for containment and cleaning up:

Collect mechanically.

Handling and storage

- 7.1 Precautions for safe handling

Prevent formation of dust.

Open and handle container with care.

- Information about protection against explosions and fires: Keep breathing equipment ready.

- 7.2 Conditions for safe storage, including any incompatibilities

- Storage

- Requirements to be met by storerooms and containers: No special requirements.

- Information about storage in one common storage facility: Not required.

- Further information about storage conditions:

Keep container tightly closed.

Store in cool, dry conditions in well sealed containers.

Store in a locked cabinet or with access restricted to technical experts or their assistants.

- 7.3 Specific end use(s) No further relevant information available.

Transport information

Shipping

SpecialProvisions

Shipping

Remarks

Marine transport (UN RTDG/IMDG)

Shipping

Remarks

Shipping

Remarks

SpecialProvisions

Exposure controls / personal protection

- 8.1 Control parameters

- Components with limit values that require monitoring at the workplace: Not required.

- DNELs (Derived no-effect level) No information available

- PNECs (predicted no effect concentration) No information available

- Additional information: The lists that were valid during the compilation were used as basis.

- 8.2 Exposure controls

- Personal protective equipment

- General protective and hygienic measures

The usual precautionary measures should be adhered to general rules for handling chemicals.

Keep away from foodstuffs, beverages and food.

Take off immediately all contaminated clothing

Wash hands during breaks and at the end of the work.

Store protective clothing separately.

Avoid contact with the eyes and skin.

- Breathing equipment:

In case of brief exposure or low pollution use breathing filter apparatus. In case of intensive or longer

exposure use breathing apparatus that is independent of circulating air.

- Recommended filter device for short term use:

Filter P3

- Protection of hands:

Protective gloves (EN 374).

Due to missing tests no recommendation to the glove material can be given for the product/ the preparation/

the chemical mixture.

- Material of gloves

The selection of the suitable gloves does not only depend on the material, but also on further marks of quality

and varies from manufacturer to manufacturer.

- Penetration time of glove material

The exact break trough time has to be found out by the manufacturer of the protective gloves and has to be

observed.

- Eye protection:

Tightly sealed safety glasses.

- Body protection: Protective work clothing.

Stability and reactivity

- 10.1 Reactivity No further relevant information available.

- 10.2 Chemical stability

- Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.

- 10.3 Possibility of hazardous reactions No dangerous reactions known

- 10.4 Conditions to avoid No further relevant information available.

- 10.5 Incompatible materials: Not known

- 10.6 Hazardous decomposition products: No dangerous decomposition products known

Disposal considerations

- 13.1 Waste treatment methods

- Recommendation Hand over to disposers of hazardous waste.

- Uncleaned packagings:

- Recommendation:

Disposal must be made according to official regulations.

Packaging must be disposed of in compliance with country-specific regulations or must be passed to a

packaging return system.