Registration Dossier
Registration Dossier
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EC number: 806-543-7 | CAS number: 215917-77-4
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
Only standard information required at REACH Annex VIII is available for assessing the toxicokinetics for the test substance. The available test data do not permit conclusions concerning absorption, metabolism or excretion to be drawn. Acute toxicity (via the oral and inhalation route), and repeat dose toxicity (via the oral route), were low. Appropriate physical chemical properties (relatively low Log Kow and water solubility, hydrolytic stability, a moderate molecular weight and lack of potentially ionisable groups), indicate a low potential for absorption.
Key value for chemical safety assessment
- Bioaccumulation potential:
- low bioaccumulation potential
Additional information
The available test data do not permit conclusions concerning absorption, metabolism or excretion to be drawn. Acute toxicity (via the oral and inhalation route), and repeat dose toxicity (via the oral route), were low and below the cut offs for any applicable CLP classification based on available data. No significant effects were observed in these studies to indicate that the test substance was absorbed and distributed systemically. The low water solubility (<10 mg/L), relatively low Log Kow (<3) both indicate a low potential for absorption to occur and the test material has been determined to be hydrolytically stable at a low pH (pH 4). The test material is also of a moderate molecular weight, and does not possess groups which could be potentially ionised. The test item did not show evidence of mutagenicity in the in vitro Ames test, but was positive in the in vitro chromosome aberration study.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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