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Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
comparable to guideline study
Qualifier:
according to guideline
Guideline:
other: ISO 13320: 2009
Deviations:
no
Qualifier:
according to guideline
Guideline:
other: CIPAC MT 187
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
other: diameter distribution
Type of distribution:
mass based distribution
Specific details on test material used for the study:
Batch: CDC-003
Mass median aerodynamic diameter:
51.69 µm
Key result
Percentile:
D50
Mean:
43.531 µm
Remarks on result:
other: not standard deviation
Key result
Percentile:
D10
Mean:
< 9.243 µm
St. dev.:
0.17
Key result
Percentile:
D50
Mean:
< 43.531 µm
St. dev.:
0.24
Key result
Percentile:
D90
Mean:
< 142.47 µm
St. dev.:
1.26
Conclusions:
10.65% of the sample was determined to be <10.00 µm.
MMAD was 51.69 µm.

Description of key information

Particle size was determined by laser diffraction analysis using the small volume (wet) module (SVM) with sunflower oil as the dispersant.

Additional information

10.65% of the sample was determined to be <10.00 µm.

MMAD was 51.69 µm.